Results 101 to 110 of about 7,453,208 (377)
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
The induction of autophagy by mechanical stress [PDF]
Autophagy, 2011 The ability to respond and adapt to changes in the physical environment is a universal and essential cellular property. Here we demonstrated that cells respond to mechanical compressive stress by rapidly inducing autophagosome formation. We measured this response in both Dictyostelium and mammalian cells, indicating that this is an evolutionarily ...
Douwe M. Veltman +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Finite element analysis of the interface defect in ceramic-metal assemblies: Alumina-Silver
Fracture and Structural Integrity, 2020 In the present work, the finite element analysis was employed to study the distribution of mechanical stress generated in metal-ceramic bimaterial.
Lamia Hadid +3 more
doaj +1 more source
eLife, 2015 The role of mechanical signals in cell identity determination remains poorly explored in tissues. Furthermore, because mechanical stress is widespread, mechanical signals are difficult to uncouple from biochemical-based transduction pathways.
Benoît Landrein +12 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Discussion: “A Mechanical Analyzer for Computing Transient Stresses in Airplane Structures” (Bisplinghoff, R. L., Pian, T. H. H., and Levy, L. I., 1950, ASME J. Appl. Mech., 17, pp. 310–314) [PDF]
, 1951 Robert H. Scanlan
openalex +3 more sources
Variability of the local φMS values over the gate area of MOS devices
Journal of Telecommunications and Information Technology, 2005 The local value distributions of the effective contact potential difference (ECPD or the φMS factor) over the gate area of Al-SiO2-Si structures were investigated for the first time.
Henryk M. Przewłock +3 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Membrane Deflection and Stress in Thermal Flow Sensors
Proceedings, 2018 The effect of membrane deflection has been investigated for thermal flow sensors. Catastrophic membrane breakage is a common occurrence in membrane based thermal flow sensors due to thermal expansion and internal stresses.
Claudio Falco +5 more
doaj +1 more source