Results 111 to 120 of about 7,453,208 (377)
π-extended anthracenes as sensitive probes for mechanical stress
Diels–Alder adducts of π-extended anthracenes have been synthesised, employed as mechanophores in polymeric materials and show unprecedented detection sensitivity for mechanical stress.
R. Göstl, R. Sijbesma
semanticscholar +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Microtubules self-repair in response to mechanical stress
Microtubules - which define the shape of axons, cilia and flagella, and provide tracks for intracellular transport - can be highly bent by intracellular forces, and microtubule structure and stiffness are thought to be affected by physical constraints ...
Laura Schaedel+5 more
semanticscholar +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
Introduction: Nowadays, Snap-fits have many applications in the automotive industry, especially in assembly lines. They are used instead of the mechanical joints such as bolts, the cabling joints, and the car interior lining joints.
Hamed Salmanzadeh, Zohreh Shakeri Kebria
doaj
BACKGROUND Biochemical alterations associated with mechanical stress have been explored as an initiating step in the pathological progression of ligamentum flavum hypertrophy (LFH); however, this mechanism remains poorly understood.
Junseok W. Hur+6 more
semanticscholar +1 more source
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
Time-independent Anisotropic Plastic Behavior by Mechanical Subelement Models [PDF]
The paper describes a procedure for modelling the anisotropic elastic-plastic behavior of metals in plane stress state by the mechanical sub-layer model.
Pian, T. H. H.
core +1 more source
Plasma Membrane Mechanical Stress Activates TRPC5 Channels
Mechanical forces exerted on cells impose stress on the plasma membrane. Cells sense this stress and elicit a mechanoelectric transduction cascade that initiates compensatory mechanisms.
B. Shen+6 more
semanticscholar +1 more source