Results 151 to 160 of about 1,697,500 (308)

Advanced thermoplastic resins, phase 1 [PDF]

Eight thermoplastic polyimide resin systems were evaluated as composite matrix materials. Two resins were selected for more extensive mechanical testing and both were versions of LaRC-TPI (Langley Research Center - Thermoplastic Polyimide). One resin was
Falcone, A., Gerken, N. T., Hendricks, C. L., Hill, S. G.   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A Miniaturized Device Coupled with Digital Image Correlation for Mechanical Testing. [PDF]

Micromachines (Basel), 2022
Cruz DJ, Xavier J, Amaral RL, Santos AD.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessing biocompatibility & mechanical testing of 3D-printed PEEK versus milled PEEK. [PDF]

Heliyon, 2022
Limaye N, Veschini L, Coward T.
europepmc   +1 more source

Improved techniques for thermomechanical testing in support of deformation modeling [PDF]

The feasibility of generating precise thermomechanical deformation data to support constitutive model development was investigated. Here, the requirement is for experimental data that is free from anomalies caused by less than ideal equipment and ...
Castelli, Michael G., Ellis, John R.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Experimental Investigation on the Performance of Full Tailings Cemented Backfill Material in a Lead-Zinc Mine Based on Mechanical Testing. [PDF]

Materials (Basel)
Yang N, Ou R, Bu R, Sun D, Yan F, Wang H, Liu Q, Tang M, Li X.   +8 more
europepmc   +1 more source

Circular Production, Designing, and Mechanical Testing of Polypropylene-Based Reinforced Composite Materials: Statistical Analysis for Potential Automotive and Nuclear Applications. [PDF]

Polymers (Basel), 2023
Hussain A, Podgursky V, Goljandin D, Antonov M, Sergejev F, Krasnou I.   +5 more
europepmc   +1 more source