Results 171 to 180 of about 1,690,858 (288)

Density-Based Topology-Optimized 3D-Printed Fixtures for Cyclic Mechanical Testing of Lattice Structures. [PDF]

open access: yesPolymers (Basel)
Castro J   +6 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Experimental datasets from mechanical testing and characterization of composites filled with PVCs waste. [PDF]

open access: yesData Brief
Nugraha AD   +7 more
europepmc   +1 more source

Mechanical testing of transtibial prosthetic sockets: A discussion paper from the American Orthotic and Prosthetic Association Socket Guidance Workgroup. [PDF]

open access: yesProsthet Orthot Int, 2023
Gariboldi F   +8 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Multimodal Evaluation of Three NiTi Rotary Systems: Clinical Simulation, Mechanical Testing, and Finite Element Analysis. [PDF]

open access: yesDent J (Basel)
Aparicio JA   +8 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

A Comprehensive Mechanical Testing of Polyacrylamide Hydrogels: The Impact of Crosslink Density. [PDF]

open access: yesPolymers (Basel)
Antipova CG   +7 more
europepmc   +1 more source

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