Results 1 to 10 of about 10,934,015 (395)

Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model

open access: yesAMB Express, 2021
Bacterial biofilms formation is one of the major reasons for treatment failure in chronic wound infections. Therefore, diagnostic biomarkers remain the best option for prevention and treatment of chronic wound infections by biofilms.
Xiaojuan Tan   +6 more
doaj   +1 more source

Mechanics in biology [PDF]

open access: yesEurophysics News, 2020
Mechanics plays a key role in life, from simple tasks like providing protective shielding to highly complex ones such as cell division. To understand mechanical properties on the organism level, we need to zoom in to its constituent cells, then zoom back out to see how they collectively build tissues.
openaire   +3 more sources

In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation

open access: yesGenome Biology, 2023
Background Harnessing hepatocytes for basic research and regenerative medicine demands a complete understanding of the genetic determinants underlying hepatocyte differentiation and maturation.
Junbo Liang   +11 more
doaj   +1 more source

SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been posing great threats to the world in many aspects. Effective therapeutic and preventive approaches including drugs and vaccines are still unavailable although
Mei-Yue Wang   +5 more
semanticscholar   +1 more source

Proteomic and functional profiling of platelet-derived extracellular vesicles released under physiological or tumor-associated conditions

open access: yesCell Death Discovery, 2022
During hemostasis, thrombosis, and inflammation, activated blood platelets release extracellular vesicles (PEVs) that represent biological mediators of physiological and pathological processes.
Mauro Vismara   +8 more
doaj   +1 more source

Homeostasis as the Mechanism of Evolution. [PDF]

open access: yes, 2015
Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
core   +2 more sources

Epigenetics: Biology's Quantum Mechanics [PDF]

open access: yesFrontiers in Plant Science, 2011
The perspective presented here is that modern genetics is at a similar stage of development as were early formulations of quantum mechanics theory in the 1920s and that in 2010 we are at the dawn of a new revolution in genetics that promises to enrich and deepen our understanding of the gene and the genome. The interrelationships and interdependence of
openaire   +3 more sources

Making serine integrases work for us [PDF]

open access: yes, 2017
DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core   +1 more source

Toward Mechanical Systems Biology in Bone [PDF]

open access: yesAnnals of Biomedical Engineering, 2012
ISSN:1573 ...
Trüssel, Andreas   +2 more
openaire   +3 more sources

Studies on the cold tolerance of ratoon ‘Chaling’ common wild rice

open access: yesBiological Research, 2020
Background Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress.
Mengliang Xu   +5 more
doaj   +1 more source

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