Results 31 to 40 of about 10,501,738 (419)
Mechanical and Systems Biology of Cancer
Computational and Structural Biotechnology Journal, 2018 18 pages, 3 ...
Fabian Spill, Chris Bakal, Michael Mak
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Circulating markers of ageing and allostatic load: a slow train coming [PDF]
, 2017 Dealing with the growing burden of age-related morbidities is one of the greatest challenges facing modern society. How we age across the lifecourse and how psychosocial and lifestyle factors interplay with the biology of ageing remains to be fully ...
Kooman, Jeroen P. +3 more
core +2 more sources
Epigenetics: Biology's Quantum Mechanics [PDF]
Frontiers in Plant Science, 2011 The perspective presented here is that modern genetics is at a similar stage of development as were early formulations of quantum mechanics theory in the 1920s and that in 2010 we are at the dawn of a new revolution in genetics that promises to enrich and deepen our understanding of the gene and the genome. The interrelationships and interdependence of
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The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. [PDF]
, 2016 Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across multiple tumour types. However, to date, cancer profiling has largely focused on protein-coding genes, which
Backofen, Rolf +27 more
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A clickable oxysterol photolabel retains NMDA receptor activity and accumulates in neurons [PDF]
, 2018 Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear.
Benz, Ann +6 more
core +3 more sources
Three facets of mathematical cancer biology research [PDF]
arXiv, 2023 Cancer, as the uncontrollable cell growth, is related to many branches of biology. In this review, we will discuss three mathematical approaches for studying cancer biology: population dynamics, gene regulation, and developmental biology. If we understand all biochemical mechanisms of cancer cells, we can directly calculate how the cancer cell ...
arxiv
Ferroptosis: mechanisms, biology and role in disease
Nature Reviews Molecular Cell Biology, 2021 The research field of ferroptosis has seen exponential growth over the past few years, since the term was coined in 2012. This unique modality of cell death, driven by iron-dependent phospholipid peroxidation, is regulated by multiple cellular metabolic pathways, including redox homeostasis, iron handling, mitochondrial activity and metabolism of amino
Xuejun Jiang +2 more
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Molecular mechanisms of telomere biology disorders [PDF]
Journal of Biological Chemistry, 2021 Genetic mutations that affect telomerase function or telomere maintenance result in a variety of diseases collectively called telomeropathies. This wide spectrum of disorders, which include dyskeratosis congenita, pulmonary fibrosis, and aplastic anemia, is characterized by severely short telomeres, often resulting in hematopoietic stem cell failure in
Sherilyn Grill, Jayakrishnan Nandakumar
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Nature Communications, 2020 Water intake is critical to our life, and the subfornical organ in the brain involved in the control of this behavior. Here, the authors reveal that two distinct groups of CCK-producing neurons in the SFO suppress water intake according to the ...
Takashi Matsuda +4 more
doaj +1 more source
Biology helps you to win a game [PDF]
Physica Scripta T106, 32 (2003), 2003 We present a game of interacting agents which mimics the complex dynamics found in many natural and social systems. These agents modify their strategies periodically, depending on their performances using genetic crossover mechanisms, inspired by biology. We study the performances of the agents under different conditions, and how they adapt themselves.
arxiv +1 more source