Results 51 to 60 of about 2,572,200 (301)
Mathematics at the eve of a historic transition in biology
, 2017 A century ago physicists and mathematicians worked in tandem and established quantum mechanism. Indeed, algebras, partial differential equations, group theory, and functional analysis underpin the foundation of quantum mechanism.
Wei, Guo-Wei
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter. [PDF]
, 2018 Sodium (Na+) is a ubiquitous and important inorganic salt mediating many critical biological processes such as neuronal excitation, signaling, and facilitation of various transporters.
Gonen, Tamir, Liu, Shian
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Molecular Architecture and Biological Reactions [PDF]
, 1946 Answers to many basic problems of biology—nature of growth, mechanism of duplication of viruses and genes , action of enzymes, mechanism, of physiological activity of drugs, hormones, and vitamins, structure and action of nerve and brain tissue—may ...
Pauling, Linus
core
Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]
, 2016 The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (
Chou, Tom +2 more
core +3 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Inter-Tunneling Mechanism of Colliding Population Waves [PDF]
, 2012 Here we show a new interaction mechanism of colliding population waves. It provides a stable coexistence of two similar but different species competing for the same limiting resource during their asexual propagation in a limited homogeneous environment ...
Lev V. Kalmykov, Vyacheslav L. Kalmykov
core +1 more source
Monte Carlo study of gating and selection in potassium channels
, 2011 The study of selection and gating in potassium channels is a very important issue in modern biology. Indeed such structures are known in all types of cells in all organisms where they play many important functional roles.
A. L. Hodgkin +6 more
core +1 more source
Localized JNK signaling regulates organ size during development. [PDF]
, 2016 A fundamental question of biology is what determines organ size. Despite demonstrations that factors within organs determine their sizes, intrinsic size control mechanisms remain elusive.
Beachy, Philip A +5 more
core +3 more sources