Results 21 to 30 of about 997,241 (253)

Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery

Nature Communications, 2022
The mechanism of flavivirus activation for membrane fusion is not yet understood. Here, Vaney et al. describe how the viral pr protein, derived from an HSP40/DnaJ chaperonin, interacts with a pH sensing loop in the envelope protein E for fusogenic ...
Marie-Christine Vaney, Mariano Dellarole, Stéphane Duquerroy, Iris Medits, Georgios Tsouchnikas, Alexander Rouvinski, Patrick England, Karin Stiasny, Franz X. Heinz, Félix A. Rey   +9 more
doaj   +1 more source

Extremum-Seeking Control for a Class of Mechanical Systems [PDF]

IEEE Transactions on Automatic Control, 2023
We present a novel extremum seeking method for affine connection mechanical control systems. The proposed control law involves periodic perturbation signals with sufficiently large amplitudes and frequencies. A suitable averaging analysis reveals that the solutions of the closed-loop system converge locally uniformly to the solutions of an averaged ...
openaire   +2 more sources

ON NEW CLASS OF PARALLEL-CROSS MECHANISMS [PDF]

, 2009
This paper addresses the new parallel-cross mechanisms, their classification and analysis. Several crossing kinematic chains of these mechanisms are located between the parallel kinematic chains. The contribution concerning to these mechanisms is their more large workspace than this of parallel mechanisms.
Arakelian, Vigen, Glazunov, Victor, Briot, Sébastien, Nguyen, Min Tanh   +3 more
openaire   +2 more sources

On the Security of a Class of Diffusion Mechanisms for Image Encryption [PDF]

IEEE Transactions on Cybernetics, 2018
16 pages, 7 ...
Zhang, Leo Yu, Liu, Yuansheng, Pareschi, Fabio, Zhang, Yushu, Wong, Kwok-Wo, Rovatti, Riccardo, Setti, Gianluca   +6 more
openaire   +7 more sources

Structural analysis of a third-class ten-link mechanism with two complex links

Trudy Odesskogo Politehničeskogo Universiteta
The basis of a technological machine is a mechanism whose main task is to convert the predetermined mechanical motion of the moving link of the initial mechanism into the motion of the driven link required to perform a technological operation, with the ...
Сергій Олександрович Кошель, Ганна Володимирівна Кошель, Марк Геннадійович Залюбовський, Сергій Анатолійович Поповіченко, Олександр Сергійович Кошель   +4 more
doaj   +5 more sources

Dynamics and control of a class of underactuated mechanical systems [PDF]

IEEE Transactions on Automatic Control, 1999
Summary: This paper presents a theoretical framework for the dynamics and control of underactuated mechanical systems, defined as systems with fewer inputs than degrees of freedom. Control system formulation of underactuated mechanical systems is addressed and a class of underactuated systems characterized by nonintegrable dynamics relations is ...
Mahmut Reyhanoglu, Arjan van der Schaft, N. Harris McClamroch, Ilya V. Kolmanovsky   +3 more
openaire   +3 more sources

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source