Results 91 to 100 of about 23,050,020 (302)

An Improved Measurement Uncertainty Calculation Method of Profile Error for Sculptured Surfaces

open access: yesChinese Journal of Mechanical Engineering, 2019
The current researches mainly adopt “Guide to the expression of uncertainty in measurement (GUM)” to calculate the profile error. However, GUM can only be applied in the linear models.
Chenhui Liu   +3 more
doaj   +1 more source

A Theory of Crowdfunding - A Mechanism Design Approach with Demand Uncertainty and Moral Hazard

open access: yesSocial Science Research Network, 2017
Crowdfunding provides innovation in that it enables entrepreneurs to contract with consumers before investment. Under aggregate demand uncertainty, this improves screening for valuable projects.
Roland Strausz
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Mechanism design for a fair and equitable approach to global vaccine distribution: The case of COVID-19. [PDF]

open access: yesPLOS Glob Public Health, 2023
Abedrabboh K   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Mechanism design for pandemics. [PDF]

open access: yesRev Econ Des, 2022
Maskin E.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A New Skeleton Model and the Motion Rhythm Analysis for Human Shoulder Complex Oriented to Rehabilitation Robotics

open access: yesApplied Bionics and Biomechanics, 2018
Rehabilitation robotics has become a widely accepted method to deal with the training of people with motor dysfunction. In robotics medium training, shoulder repeated exercise training has been proven beneficial for improving motion ability of human ...
Song Zhibin   +3 more
doaj   +1 more source

Force/Torque Sensorless Compliant Control Strategy for Assembly Tasks Using a 6-DOF Collaborative Robot

open access: yesIEEE Access, 2019
The flexibility of the robot assembly process is critical, and a robot assembly system that is not flexible may damage the workpieces. Most researchers make the assembly process flexible by installing a six-dimensional force/torque sensor at the end of ...
Fan Zeng, Juliang Xiao, Haitao Liu
doaj   +1 more source

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