Results 61 to 70 of about 4,576,095 (337)

Automated Identification and Representation of System Requirements Based on Large Language Models and Knowledge Graphs

open access: yesApplied Sciences
In the product design and manufacturing process, the effective management and representation of system requirements (SRs) are crucial for ensuring product quality and consistency.
Lei Wang   +5 more
doaj   +1 more source

Vibration Sensor-Based Bearing Fault Diagnosis Using Ellipsoid-ARTMAP and Differential Evolution Algorithms

open access: yesSensors, 2014
Effective fault classification of rolling element bearings provides an important basis for ensuring safe operation of rotating machinery. In this paper, a novel vibration sensor-based fault diagnosis method using an Ellipsoid-ARTMAP network (EAM) and a ...
Chang Liu   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Earthworm-Inspired Multimodal Pneumatic Continuous Soft Robot Enhanced by Winding Transmission

open access: yesCyborg and Bionic Systems
This paper presents an earthworm-inspired multimodal pneumatic continuous soft robot enhanced by wire-winding transmission. First, a derived overlapped continuous control law based on multiple peristaltic waves is introduced to effectively improve the ...
Jianbin Liu   +4 more
doaj   +1 more source

A Muscle-Specific Rehabilitation Training Method Based on Muscle Activation and the Optimal Load Orientation Concept

open access: yesApplied Bionics and Biomechanics, 2018
Training based on muscle-oriented repetitive movements has been shown to be beneficial for the improvement of movement abilities in human limbs in relation to fitness, athletic training, and rehabilitation training.
Zhibin Song   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A mapping model between the workpiece geometric tolerance and the end pose error of CNC machine tool considering structure distortion of cutting process system

open access: yesAdvances in Mechanical Engineering, 2021
Aiming at the problem that the geometric accuracy design index of machine tools is difficult to be determined reasonably in the geometric precision design process of CNC machine tools, this paper presents a mapping model between geometric tolerance of ...
Zixin Lin   +4 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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