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Study on the mechanism of action of HuaZhuoKeLi in modulating LCN2-mediated cellular pyroptosis to ameliorate ulcerative colitis. [PDF]
Sci RepYang L +7 more
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Analysis of the efficacy and mechanism of action of Buzhong Yiqi Decoction on gastric cancer using meta-analysis and network pharmacology. [PDF]
Medicine (Baltimore)Yang R, Wu Y, Tao C, Lin X, Jiang R.
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Mechanisms of action of nitrates
Cardiovascular Drugs and Therapy, 1994Glyceryl trinitrate, isosorbide dinitrate, and isosorbide-5-mononitrate are organic nitrate esters commonly used in the treatment of angina pectoris, myocardial infarction, and congestive heart failure. Organic nitrate esters have a direct relaxant effect on vascular smooth muscles, and the dilation of coronary vessels improves oxygen supply to the ...
K E, Torfgård, J, Ahlner
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Bisphosphonate mechanism of action
Current Rheumatology Reports, 2002Nitrogen-containing bisphosphonates (N-BPs) are potent inhibitors of bone resorption widely used in the treatment of osteoporosis and other bone degrading disorders. At the tissue level, N-BPs reduce bone turnover, increase bone mass and mineralization, measured clinically as a rise in bone mineral density, increase bone strength and reduce fracture ...
Alfred A, Reszka, Gideon A, Rodan
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Hydroxyurea: Mechanism of Action
Science, 1963Acetohydroxamic acid has been identified, by paper chromatography, in the blood of three patients with chronic myelogenous leukemia on hydroxyurea therapy. This suggests that the drug is hydrolyzed yielding hyroxylamine, which then cleaves thioesters, in particular acetyl-coenzyme A.
W N, FISHBEIN, P P, CARBONE
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Mechanism of action of dipyridamole
Thrombosis Research, 1983Dipyridamole appears to act in vivo by synergistically modifying several biochemical pathways, including: a) inhibition of platelet cAMP-phosphodiesterase; b) potentiation of adenosine inhibition of platelet function by blocking reuptake by vascular and blood cells, and subsequent degradation of adenosine; and possibly, c) potentiation of PGI2 ...
L A, Harker, R A, Kadatz
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The mechanism of action of probiotics
Current Opinion in Gastroenterology, 2007Probiotics are a heterogeneous group of nonpathologic bacteria that are functionally defined by their ability to allay inflammation when introduced into the inflamed intestine. The purpose of this review is to discuss recent data bearing on the possible mechanisms of action of these bacteria, with a particular focus on the relation of these mechanisms ...
Monica, Boirivant, Warren, Strober
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The mechanism of action of insulin
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1955At the present time when the chemical exploration of the insulin molecule has yielded spectacular results (257–259) the physiology of its action is still a matter of speculation. Yet in this field, too, much new knowledge has been gained, mainly by the application of new techniques, such as the use of isotopes and in vitro studies with surviving ...
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Mechanism of Action of Pseudomycins
Giornale botanico italiano, 1995(1995). Mechanism of Action of Pseudomycins. Giornale botanico italiano: Vol. 129, No. 4, pp. 1056-1057.
Di Giorgio D. +3 more
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