Results 21 to 30 of about 4,146,035 (404)

A review: Mechanism of action of antiviral drugs

open access: yesInternational Journal of Immunopathology and Pharmacology, 2021
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections. Drugs that combat viral infections are called antiviral drugs. Viruses are among the major pathogenic agents that cause number of serious diseases in humans,
S. Kausar   +9 more
semanticscholar   +1 more source

Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action

open access: yesInternational Journal of Molecular Sciences, 2020
Cannabis has a long history of medical use. Although there are many cannabinoids present in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two components found in the highest concentrations.
J. Mlost, M. Bryk, K. Starowicz
semanticscholar   +1 more source

Characterization of Properties and Transglycosylation Abilities of Recombinant α-Galactosidase from Cold-Adapted Marine Bacterium Pseudoalteromonas KMM 701 and Its C494N and D451A Mutants

open access: yesMarine Drugs, 2018
A novel wild-type recombinant cold-active α-d-galactosidase (α-PsGal) from the cold-adapted marine bacterium Pseudoalteromonas sp. KMM 701, and its mutants D451A and C494N, were studied in terms of their structural, physicochemical, and ...
Irina Bakunina   +8 more
doaj   +1 more source

Role of AMP-activated protein kinase in mechanism of metformin action.

open access: yesJournal of Clinical Investigation, 2001
Metformin is a widely used drug for treatment of type 2 diabetes with no defined cellular mechanism of action. Its glucose-lowering effect results from decreased hepatic glucose production and increased glucose utilization. Metformin's beneficial effects
Gaochao Zhou   +13 more
semanticscholar   +1 more source

Bisphosphonates: Mechanisms of Action [PDF]

open access: yesEndocrine Reviews, 1998
The geminal bisphosphonates are a class of drug, developed in the last 30 years, characterised by a P-C-P bond. Consequently, they are analogues of pyrophosphate but are resistant to chemical and enzymatic hydrolysis. The bisphosphonates bind strongly to hydroxyapatite crystals and inhibit their formation and dissolution. This physicochemical effect on
openaire   +5 more sources

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.

open access: yesPhysiological Reviews, 2016
1,25-Dihydroxvitamin D3 [1,25(OH)2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)2D3 action involves the direct binding of the 1,25(OH)2D3 activated vitamin D receptor/retinoic X receptor (VDR/RXR) heterodimeric complex ...
S. Christakos   +4 more
semanticscholar   +1 more source

Silver Nanoparticles: Mechanism of Action and Probable Bio-Application

open access: yesJournal of Functional Biomaterials, 2020
This review is devoted to the medical application of silver nanoparticles produced as a result of “green” synthesis using various living organisms (bacteria, fungi, plants).
E. O. Mikhailova
semanticscholar   +1 more source

Health Benefits and Pharmacological Properties of Carvone

open access: yesBiomolecules, 2021
Carvone is a monoterpene ketone contained in the essential oils of several aromatic and medicinal plants of the Lamiaceae and Asteraceae families. From aromatic plants, this monoterpene is secreted at different concentrations depending on the species ...
Abdelhakim Bouyahya   +9 more
doaj   +1 more source

The mechanisms of action of metformin [PDF]

open access: yesDiabetologia, 2017
Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying these benefits are complex and still not fully understood. Physiologically, metformin has been shown to reduce hepatic glucose production, yet not all of its effects can be explained by this ...
Rena, Graham   +2 more
openaire   +3 more sources

Neuroprotective Activity of Some Marine Fungal Metabolites in the 6-Hydroxydopamin- and Paraquat-Induced Parkinson’s Disease Models

open access: yesMarine Drugs, 2018
A new melatonin analogue 6-hydroxy-N-acetyl-β-oxotryptamine (1) was isolated from the marine-derived fungus Penicillium sp. KMM 4672. It is the second case of melatonin-related compounds isolation from microfilamentous fungi.
Ekaterina A. Yurchenko   +6 more
doaj   +1 more source

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