Results 61 to 70 of about 3,910,323 (355)
Sodium-glucose co-transporter 2 inhibitor therapy: mechanisms of action in heart failure [PDF]
, 2021 Shruti Joshi +3 more
openalex +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Hydroxychloroquine: a comprehensive review and its controversial role in coronavirus disease 2019
Annals of Medicine, 2021 Hydroxychloroquine, initially used as an antimalarial, is used as an immunomodulatory and anti-inflammatory agent for the management of autoimmune and rheumatic diseases such as systemic lupus erythematosus.
Pankaj Bansal +13 more
doaj +1 more source
Interacting branes, dual branes, and dyonic branes: a unifying lagrangian approach in D dimensions [PDF]
, 2000 This paper presents a general covariant lagrangian framework for the dynamics of a system of closed n-branes and dual (D-n-4)-branes in D dimensions, interacting with a dynamical (n+1)-form gauge potential.
Lechner, K., Marchetti, P. A.
core +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Sulodexide. Pharmacokinetics, pharmacodynamics, and mechanism of action
Clinical Management Issues, 2015 Sulodexide is a highly purified preparation containing glycosaminoglycans composed from heparin-like and dermatan fractions. It is similar to unfractionated heparin, but it shows a prolonged half-life, a higher bioavability and a reduced effect on ...
Luca Masotti
doaj +1 more source
Quantum generation of Schwarzschild-de Sitter (Nariai) black holes in effective dilaton-Maxwell gravity [PDF]
, 1998 Dilaton coupled electromagnetic field is essential element of low-energy string effective action or it may be considered as result of spherical compactification of Maxwell theory in higher dimensions.
Andrei A. Bytsenko +6 more
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
MECHANISM OF ACTIONS OF ANTIDEPRESSANTS: BEYOND THE RECEPTORS
Psychiatry and Clinical Psychopharmacology, 2021 Since the discovery of first antidepressants-monoamine oxidase inhibitors- a half century passed. There are now almost twodozen antidepressant agents that work by nine distinct pharmacological mechanisms at the receptor level.
Ayşegül Yıldız +2 more
doaj
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source