Results 61 to 70 of about 165,714 (281)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Assessment of mechanization status for some major crop value chains in Ghana

open access: yesAcademy Journal of Science and Engineering, 2023
Mechanization of agriculture is widely accepted as a means to raise agricultural output and ensure sufficient food supplies. Previous failed attempts to mechanize Ghana's agriculture have been linked to a failure on the part of policymakers to recognize ...
Patricia Amankwaa-Yeboah   +7 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effects of Agricultural Mechanization on Farm Income Patterns [PDF]

open access: yes
This article is part of the seminar-workshop on the “Consequences of Small Farm Mechanization on Production, Employment and Incomes in the Philippines” sponsored jointly by the Ministry of Agriculture, the National Economic and Development Authority, the
Lim, Pilar C.
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Sistema informativo de operação em campo agrícola, baseado na aquisição automática de dados An information system based on automatic data recording

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2001
Este trabalho apresenta uma proposta de desenvolvimento de um sistema informativo, projetado especificamente para o levantamento dos dados operacionais no campo, o que visa ao gerenciamento da informação na propriedade agrícola.
Gastão M. da Silveira   +2 more
doaj   +1 more source

Mechanization, Automation, Robotization and Digitalization: Conceptual Clarification and Systematization

open access: yesСельскохозяйственные машины и технологии, 2023
The paper highlights the importance of clarifying scientific terminology to delineate the exclusion of humans from technical systems, in particular the concepts such as «mechanization,» «automation,» «robotization,» and «digitalization» that are commonly
V. M. Korotchenya
doaj   +1 more source

Determinants of Farm Mechanization in Nepal

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2019
The paper attempts to explore the factors affecting the farm mechanization in Nepal, where agriculture is the primary livelihood of most people and the mechanization is crucial for efficient production and productivity. The government has also introduced
Arun GC, Jun-Ho Yeo, Kiran Ghimire
doaj   +1 more source

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