Results 101 to 110 of about 11,668 (212)

Resilient Biophysical Phenotype of Memory CD4+ T Cells in Long‐Lived Mice

Immunology, EarlyView.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega, Blanca González‐Bermúdez, Judith Félix‐Escalera, Mónica González‐Sánchez, Enzo Brito, Mónica De la Fuente, Gustavo R. Plaza   +6 more
wiley   +1 more source

The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration

Journal of Periodontal Research, EarlyView.
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung, Navya Chalamalasetty, Ali Alzainal, Hanlong Liu, Lexuan Wang, Pietra Colacrai Arikita, Ivy C. X. Wei, Hom‐Lay Wang, M. H. J. van den Bosch, Michelle S. Caird, Peter M. van der Kraan, Kenneth M. Kozloff, Esmeralda Blaney Davidson   +12 more
wiley   +1 more source

An Analysis of Wrist Motions During Daily Activities From a Directional Perspective: The Significance of Directions Beyond the Dart‐Throwing Motion

Orthopaedic Surgery, Volume 17, Issue 5, Page 1486-1502, May 2025.
The study using an optical capture system revealed the directional characteristics of wrist functional motion. The results highlighted the directional range of motion (ROM), differences in preferences between genders and age groups, and identified three key directions most frequently utilized. ABSTRACT Background Previous studies on Activities of Daily
Qipei Wei, Shijie Jia, Shengfang Zhang, Xiaofeng Qiao, Zhixin Wang, Chang Liu, Shanlin Chen   +6 more
wiley   +1 more source

Matrix Viscoelasticity: The Overlooked Architect of Solid Tumour Evolution

Organ Medicine, EarlyView.
Ruixi Huang, Yupeng Guan
wiley   +1 more source

Physical activity and joint health: Implications for knee osteoarthritis disease pathophysiology and mechanics

Experimental Physiology, EarlyView.
Abstract Knee osteoarthritis is experienced by hundreds of millions of people worldwide and is a major cause of disability. Although enhancing physical activity levels and the participation in exercise programmes has been proved to improve the debilitating illness of osteoarthritis, many do not engage in recommended levels of physical activity.
Karl Morgan, Joshua Carter, Dario Cazzola, Jean‐Philippe Walhin   +3 more
wiley   +1 more source

Cortical dynamics of cold exposure and thermal recovery: Evidence from EEG‐based spatiotemporal analysis

Experimental Physiology, EarlyView.
Abstract Human thermal perception involves complex and dynamic interactions between peripheral input and central neural regulation. However, the spatial and temporal characteristics of brain responses to different cold exposure scenarios remain poorly understood. In this study, we combined traditional analysis with AI‐based anomaly detection to examine
Qing Zhang, Hetian Feng, Tian Liu, Jiaqi Zhou, Jingya Zheng, Junzhao Zhang, Li Ding, Jiachen Nie   +7 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

The epidermis coordinates multi-scale symmetry breaking in chiral root growth

Nature Communications
Twisted growth serves myriad adaptive functions in plants. Unlike animal motions, plant motions require symmetry breaking during growth and typically involve microtubule-related genes.
Natasha Nolan, Leila Jaafar, Yuanwei Fan, Yuxuan Huang, Lily Murchison, Juliana Ocasio, Joyce G. Onyenedum, Charles T. Anderson, Guy M. Genin, Ram Dixit   +9 more
doaj   +1 more source

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
(1) Tuina's mechanical forces activate cellular mechanosensors; (2) Induce multi‐tissue exosome release to mediate intercellular communication; (3) Exosomes systemically regulate muscle, nerve, immune and vascular functions; (4) Target gene knockout confirms exosomes’ specific mediating role.
Lifen Zhan, Ji Zhang, Yiping Chen, Suyu Chen, Xiantao Tai   +4 more
wiley   +1 more source

Disciplinary faculty's curriculum‐embedded writing‐for‐publication instruction for graduate students: A systematic review

Review of Education, Volume 14, Issue 1, April 2026.
Abstract Graduate students across the world are increasingly required or expected to publish in English‐medium academic journals, yet their capacity to do so often depends on the nature of pedagogical support available within their programs. While English for Research Publication Purposes (ERPP) instruction by language specialists has gained a growing ...
Yongyan Li, Xiaoling Liu, Wenxin Zhou
wiley   +1 more source