Results 11 to 20 of about 11,668 (212)
Endothelial mechanobiology [PDF]
Lining the luminal surface of the vasculature, endothelial cells (ECs) are in direct contact with and differentially respond to hemodynamic forces depending on their anatomic location.
Ming He +4 more
doaj +3 more sources
The growing obesity epidemic necessitates increased research on adipocyte and adipose tissue function and disease mechanisms that progress obesity. Historically, adipocytes were viewed simply as storage for excess energy.
Sean P. Blade +4 more
doaj +3 more sources
Editorial: Cardiovascular Mechanobiology [PDF]
Markus Hecker, Dirk J. Duncker
doaj +4 more sources
Keratocyte mechanobiology [PDF]
In vivo, corneal keratocytes reside within a complex 3D extracellular matrix (ECM) consisting of highly aligned collagen lamellae, growth factors, and other extracellular matrix components, and are subjected to various mechanical stimuli during developmental morphogenesis, fluctuations in intraocular pressure, and wound healing.
W Matthew, Petroll +2 more
openaire +2 more sources
Osteocyte Mechanobiology [PDF]
Over the past decades, osteocytes have emerged as mechano-sensors of bone and master regulators of bone homeostasis. This article summarizes latest research and progress made in understanding osteocyte mechanobiology and critically reviews tools currently available to study these cells.Whereas increased mechanical forces promote bone formation ...
Yuhei, Uda +4 more
openaire +2 more sources
Mechanobiology of Ciliogenesis [PDF]
Cilia are force-generating and -sensing organelles that serve as mechanical interfaces between the cell and the extracellular environment. Cilia are present in tissues that adaptively respond to mechanical loading and fluid flow, and defects in ciliary function can lead to diseases affecting these tissues.
Ishikawa, Hiroaki, Marshall, Wallace F
openaire +4 more sources
Mechanobiology of cancerogenesis
Within the tumour microenvironment, tumour cells are exposed to different mechanical stimuli such as compression stress, cell-cell and cell-extracellular matrix traction forces, interstitial fluid pressure, and shear stress. Cells actively sense and process this information by the mechanism of mechanotransduction to make decisions about their growth ...
Martina, Raudenská +3 more
openaire +2 more sources
Lung organoids have emerged as powerful tools for studying lung distal diseases by recapitulating the cellular diversity and microenvironment of the lung tissue. This review article highlights the advancements in leveraging mechanobiology and biophysical
Ziming Shao +3 more
doaj +1 more source
A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology
Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate.
Ian L. Chin +3 more
doaj +1 more source
Modelling cartilage mechanobiology [PDF]
The growth, maintenance and ossification of cartilage are fundamental to skeletal development and are regulated throughout life by the mechanical cues that are imposed by physical activities. Finite element computer analyses have been used to study the role of local tissue mechanics on endochondral ossification patterns, skeletal morphology and ...
Dennis R, Carter, Marcy, Wong
openaire +2 more sources

