Results 31 to 40 of about 11,668 (212)
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Nature Communications, 2019 Fiolopodia are involved in cell migration and their attachment to the ECM is mediated by integrin receptors. Here the authors show that myosin X induced filipodia adhesion to fibronectin requires activity of myosin IIA at the filopodium base and formin ...
N. O. Alieva +12 more
doaj +1 more source
Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells
Nature Communications, 2017 OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm.
Smarajit Chakraborty +4 more
doaj +1 more source
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis
Frontiers in Cell and Developmental Biology, 2022 The formation of functional eggs (oocyte) in ovarian follicles is arguably one of the most important events in early mammalian development since the oocytes provide the bulk genetic and cytoplasmic materials for successful reproduction.
Arikta Biswas +4 more
doaj +1 more source
Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites
Advanced Functional Materials, EarlyView.A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu +7 more
wiley +1 more source
A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
Micromachines, 2019 Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling.
Qian Feng +2 more
doaj +1 more source
Engineered hydrogels for mechanobiology
Nature Reviews Methods Primers, 2022 Cells' local mechanical environment can be as important in guiding cellular responses as many well-characterized biochemical cues. Hydrogels that mimic the native extracellular matrix can provide these mechanical cues to encapsulated cells, allowing for the study of their impact on cellular behaviours.
Ulrich Blache +8 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk +3 more
wiley +1 more source
Stimuli-responsive biomaterials for cardiac tissue engineering and dynamic mechanobiology
APL Bioengineering, 2021 Since the term “smart materials” was put forward in the 1980s, stimuli-responsive biomaterials have been used as powerful tools in tissue engineering, mechanobiology, and clinical applications.
Huaiyu Shi, Chenyan Wang, Zhen Ma
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Frontiers in Physiology, 2023 Skeletal stem and progenitor cells (SSPCs) are the multi-potent, self-renewing cell lineages that form the hematopoietic environment and adventitial structures of the skeletal tissues. Skeletal tissues are responsible for a diverse range of physiological
Seth M. Woodbury +4 more
doaj +1 more source