Results 151 to 160 of about 3,791 (174)
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Topical Mechlorethamine Therapy for Mycosis Fungoides
Archives of Dermatology, 1982Topical whole-body application of mechlorethamine hydrochloride has been shown to be efficacious in the treatment of mycosis fungoides (MF) confined to the skin. 1,2 The infiltrated plaques and tumors considerably resolve by supplementary soaks with mechlorethamine.
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Topically Applied Mechlorethamine on 12 Dermatoses
Archives of Dermatology, 1962In 1959 remission occurred in a case of mycosis fungoides following the topical application of mechlorethamine hydrochloride (a nitrogen mustard) to the lesions. 1 Since then, mechlorethamine has been used topically in additional cases of mycosis fungoides and to treat several other dermatologic disorders.
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Chemotherapy of Lymphoma With Mechlorethamine and Vinblastine
Archives of Internal Medicine, 1973To determine the relative efficacy of mechlorethamine hydrochloride and vinblastine sulfate, 172 patients with Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma were randomly assigned to receive one or the other of these agents. If treatment with the first compound failed, each patient was to be treated with the second.
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Complete Regressions of Mycosis Fungoides With Topical Mechlorethamine Hydrochloride
JAMA: The Journal of the American Medical Association, 1972Survival of patients with mycosis fungoides, a lymphoma initially appearing in the skin and thereafter spreading to internal organs, has not been substantially improved by chemotherapeutic measures in use over the past two decades. In only a few instances has the disease been reported to undergo complete regression following therapy.
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Failure to Induce Tolerance to Mechlorethamine Hydrochloride
Archives of Dermatology, 1977• In view of the contradictory results reported in the literature regarding induction of specific immunologic tolerance to mechlorethamine hydrochloride (HN2), the problem was reinvestigated using a "tolerogenic" schedule that had been reported to be effective. Mechlorethamine hydrochloride, 200 μg, intravenously, was given weekly for five weeks before
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Treatment of Hallopeau's Acrodermatitis With Topical Mechlorethamine
Archives of Dermatology, 1978To the Editor.— The therapy for Hallopeau's acrodermatitis (continua, perstans), which includes the use of common topical antipsoriatic agents like tar, cignolin, and corticosteroids, is mentioned in literature, but the extreme resistance of the disease to any therapy is well known.
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Mechlorethamine Hydrochloride Treatment of Experimental Tuberculous Uveitis
Archives of Ophthalmology, 1961The first 2 parts of this report have been presented in a previous communication. 1 Intravenous mechlorethamine hydrochloride caused no observable pathological changes in the normal rabbit eye. Treatment with intravenous mechlorethamine of infectious tuberculous uveitis in nontuberculin-sensitive rabbits showed only a temporary inhibition of the ...
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