Results 31 to 40 of about 3,272 (188)

Lack of Systemic Absorption of Topical Mechlorethamine Gel in Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma

Journal of Investigative Dermatology, 2021
Christiane Querfeld, Larisa J. Geskin, Ellen J. Kim, Julia Scarisbrick, Pietro Quaglino, Evangelia Papadavid, James T. Angello, Pablo L. Ortiz‐Romero   +7 more
openalex   +2 more sources

Topical mechlorethamine for cutaneous T-cell lymphoma: a historical perspective

EJC Skin Cancer
Balázs Nagy, Norbert Kovács, Katinka Ónodi, Ildikó Csányi, Erika Varga, Henriette Ócsai, Judit Oláh, Rolland Gyulai, Eszter Baltás   +8 more
openalex   +2 more sources

Mechlorethamine Oxide Hydrochloride [PDF]

Definitions, 2020

openalex   +2 more sources

A Retrospective Study of Chemotherapy-Related Extravasation Events in Dogs and Cats. [PDF]

J Vet Intern Med
ABSTRACT Background Chemotherapy extravasation is a potentially serious complication. There is a paucity of information in the veterinary literature investigating extravasation events, treatments, and outcomes. Objective Evaluate chemotherapy extravasation events and treatments in dogs and cats, adverse events (AEs), and overall outcomes.
Martens E, Hritz R, Clifford C, Mullin C, Camero C, Shiu KB, Chan C, Del Alcazar C, DeRegis C, Donnelly L, Marker B, Purzycka K, Vickery K.   +12 more
europepmc   +2 more sources

060 Mechlorethamine-Induced Contact Dermatitis Avoidance Study (MIDAS): Preliminary Results [PDF]

Journal of Investigative Dermatology, 2019
Elaine S. Gilmore, Carolina V. Alexander‐Savino, S. Secor-Socha, Brian Poligone   +3 more
openalex   +2 more sources

Carcinogenicity of topical mechlorethamine in mice

Journal of the American Academy of Dermatology, 1992
Herschel S. Zackheim
openalex   +3 more sources

Chlormethine Gel is Efficient and Safe in Mycosis Fungoides Skin Lesions

Acta Dermato-Venereologica, 2022
Chlormethine is a bifunctional cytotoxic alkylating agent that binds to DNA, resulting in cell death (apoptosis). Chlormethine (also known as mechlorethamine) gel (CL gel) was approved in the European Union in 2017 and was first used in 2019.
Marios Koumourtzis, Kyriaki Lampadaki, Maria Dalamaga, Evangelia Papadavid   +3 more
doaj   +1 more source

Mechlorethamine

, 2006
James L. Schardein, Orest T. Macina
europepmc   +4 more sources

NAD⁺ Acts as a Protective Factor in Cellular Stress Response to DNA Alkylating Agents

Cells, 2023
Sulfur mustard (SM) and its derivatives are potent genotoxic agents, which have been shown to trigger the activation of poly (ADP-ribose) polymerases (PARPs) and the depletion of their substrate, nicotinamide adenine dinucleotide (NAD+).
Joanna Ruszkiewicz, Ylea Papatheodorou, Nathalie Jäck, Jasmin Melzig, Franziska Eble, Annika Pirker, Marius Thomann, Andreas Haberer, Simone Rothmiller, Alexander Bürkle, Aswin Mangerich   +10 more
doaj   +1 more source

Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans

Cells, 2023
Caenorhabditis elegans (C. elegans) is gaining recognition and importance as an organismic model for toxicity testing in line with the 3Rs principle (replace, reduce, refine). In this study, we explored the use of C.
Joanna Ruszkiewicz, Lisa Endig, Ebru Güver, Alexander Bürkle, Aswin Mangerich   +4 more
doaj   +1 more source