The ASD Living Biology: from cell proliferation to clinical phenotype. [PDF]
, 2019 Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the lay public because of its uncertain origins and striking and unexplained clinical heterogeneity.
Courchesne, Eric +5 more
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MeCP2 deficiency alters the response selectivity of prefrontal cortical neurons to different social stimuli [PDF]
Natalie Boyle +10 more
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Wnt Pathway Stabilizes MeCP2 Protein to Repress PPAR-γ in Activation of Hepatic Stellate Cells
, 2016 Soo-Mi Kweon +4 more
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A mutation-led search for novel functional domains in MeCP2 [PDF]
, 2018 Jacky Guy +6 more
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Following Dynamics of Protein/Nucleic Acid Interactions in Real-Time [PDF]
, 2008 Methyl-CpG binding protein 2 (MeCP2) is a protein associated with transcriptional repression of other proteins and its various mutants are found in Rett syndrome patients, which is a severe neurodevelopmental disease found in 1/15,000 females.
Kim, Min Sun
core
Kaiso is a genome-wide repressor of transcription that is essential for amphibian development [PDF]
, 2004 Dunican, Donncha S +6 more
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Role of MeCP2, DNA methylation, and HDACs in regulating synapse function [PDF]
, 2011 Ege T. Kavalali +2 more
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MeCP2 is a general regulator of transcription involved in the repression/activation of genes depending on the local epigenetic context. It acts as a chromatin regulator and binds with exquisite specificity to gene promoters. The set of epigenetic marks recognized by MeCP2 has been already established (mainly, cytosine modifications in CpG and CpA), as ...
Ortega-Alarcon, David|| +8 more
openaire +1 more source
GlyT2-Dependent Preservation of MECP2-Expression in Inhibitory Neurons Improves Early Respiratory Symptoms but Does Not Rescue Survival in a Mouse Model of Rett Syndrome [PDF]
, 2016 Swen Hülsmann +4 more
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