Results 191 to 200 of about 27,643 (268)

Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player? [PDF]

J Neurosci Res
Lange J, Zhao E, O'Connell E, Gillham O, McTague A.   +4 more
europepmc   +1 more source

Single-cell multiome profiling reveals neuronal bias of modulatory role of MeCP2 phosphorylation. [PDF]

Neurobiol Dis
Zhang Z, Huang X, Arachchilage KH, Chandrashekar PB, Dong Q, Wang R, Wang D, Chang Q.   +7 more
europepmc   +1 more source

Extending MeCP2 interactome

MeCP2 is a general regulator of transcription involved in the repression/activation of genes depending on the local epigenetic context. It acts as a chromatin regulator and binds with exquisite specificity to gene promoters. The set of epigenetic marks recognized by MeCP2 has been already established (mainly, cytosine modifications in CpG and CpA), as ...
Ortega-Alarcon, David||, Claveria-Gimeno, Rafael, Vega, Sonia, Kalani, Ladan||, Jorge-Torres, Olga Caridad||, Esteller, M||, Ausio, Juan, Abián, Olga||, Velázquez-Campoy, Adrian||   +8 more
openaire   +1 more source

A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice

Disease Models & Mechanisms
Destynie Medeiros, Karen Ayala-Baylon, Hailey Egido-Betancourt, Eric Miller, Christopher Chapleau, Holly Robinson, Mary L. Phillips, Tao Yang, Frank M. Longo, Wei Li, Lucas Pozzo-Miller   +10 more
doaj   +1 more source

DNA methylation, nucleic acid structure, and rett mutations tune MeCP2 binding affinity and cooperativity. [PDF]

J Biol Chem
Melikishvili M, Rea M, Capan C, Lee H, Chandler DP, Fondufe-Mittendorf YN.   +5 more
europepmc   +1 more source

Anticodon-engineered tRNAs restore full-length MeCP2 expression and function in Rett syndrome nonsense mutations. [PDF]

Front Neurol
Fara E, Pezzini S, Arpaia G, Frasca A, Porter JJ, Lueck JD, Landsberger N.   +6 more
europepmc   +1 more source

Single-nucleus profiling reveals a core disease signature and cell type-specific vulnerabilities in early Rett syndrome. [PDF]

Sci Adv
Li Y, Anderson AG, Qi G, Wu SR, Revelli JP, Chen H, Liu Z, Zoghbi HY.   +7 more
europepmc   +1 more source

Astrocytic Regulation of Aberrant Perineuronal Net Formation in Mecp2-Null Neocortex. [PDF]

J Neurochem
Sinha A, Kowalchuk AM, Khatibi N, Matthews RT, MacDonald JL.   +4 more
europepmc   +1 more source

Increased Osteoclast Activity Contributes to Bone Resorption and Osteopenia in a Rett Syndrome Mouse Model. [PDF]

Cells
Samee N, Belz L, Narboux-Nême N, Roux JC, Panayotis N, Levi G.   +5 more
europepmc   +1 more source

MECP2 wt Allele [PDF]

, 2020
openaire   +1 more source