Results 191 to 200 of about 416,251 (201)

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Balancing Radiation Dose and Image Quality: Protocol Optimization for Mobile Head CT in Neurointensive Care Unit Patients. [PDF]

Diagnostics (Basel)
Mialkowskyj D, Stahl R, Heck S, Dimitriadis K, Fischer TD, Liebig T, Trumm CG, Wesemann T, Forbrig R.   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Oral Levothyroxine for Myxedema Crisis: A Case Series from a Tertiary Referral Center. [PDF]

J Endocr Soc
Arias-Valderrama O, Morales V, Arciniegas AFP, Pérez Tellez C, García AO, Guzmán Gómez GÉ, Ordóñez Giraldo JL.   +6 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Chloroprocaine ED₅₀ and ED₉₅ for Propofol Injection Pain Prevention: Dixon's Sequential Method. [PDF]

J Pain Res
Lai P, Yang X, Yang X, Xuan Q, Fang Y, He Z, Chen B, Yin G.   +7 more
europepmc   +1 more source

Dose optimization in CBCT in dentistry: a survey among EADMFR members. [PDF]

Dentomaxillofac Radiol
Fakhtei S, Hoogeveen R, Berkhout E.
europepmc   +1 more source

Rethinking Statin Dosage in Coronary Disease. [PDF]

Pharmacol Res Perspect
Dimmitt SB, Stampfer HG, Kennedy MC, Martin JH.   +3 more
europepmc   +1 more source

Prospective Dose-Finding of Esketamine for Suppressing Cervical Dilation Response in Ambulatory Hysteroscopy Under Monitored Anesthesia Care. [PDF]

Drug Des Devel Ther
Yan L, Wang X, Wei J, Zhang M, Yang B.
europepmc   +1 more source

Assessment of Radiation Dose to Adult Patients Undergoing Cardiac CT. [PDF]

Cureus
Pheroz A, Khan H, Khan A, Ahmad M, Shah MA.   +4 more
europepmc   +1 more source