A Study on the ED90 of Esketamine Combined with Ropivacaine for Early Epidural Analgesia During the First Stage of Labor in Nulliparous Women: A Randomized, Sequential Dose-Finding Trial. [PDF]
Lin X +5 more
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Radiation dose optimization in coronary CT angiography clinical application of absolute phase gating in patients with atrial fibrillation. [PDF]
Li Y.
europepmc +1 more source
Determination of the median effective dose of chloroprocaine in labour: preliminary results
Anssens, Sarah +4 more
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Interval estimation of the median effective dose for a logistic dose-response curve [PDF]
In 1986, Williams showed how, assuming a logistic dose-response curve, one can construct a confidence interval for the median effective dose from the asymptotic likelihood ratio test. He gave reasons for preferring this likelihood ratio interval to the established interval calculated by applying Fieller's theorem to the maximum-likelihood estimates ...
Peter Harris +3 more
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Median effective dose of 0.2% ropivacaine for ultrasound-guided median nerve block in young children
Anaesthesia Critical Care & Pain Medicine, 2023To determine the median effective dose (ED50) and the 95% effective dose (ED95) of 0.2% ropivacaine for ultrasound-guided lower forearm median nerve block in paediatric patients.Eligible children were American Society of Anesthesiologists (ASA) status I-II scheduled to have elective open surgery for trigger thumb repair.
Weiping Wang +10 more
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Evaluation of statistical methodologies for estimation of median effective dose
Toxicology and Applied Pharmacology, 1985A comparison is made of statistical techniques currently in use for analysis of quantal assay data. The discussion focuses on the choice of the functional model to use in the description of the tolerance distribution for the estimation of the median effective dose and in the contrast between exact and graphical methods of estimation for a given choice ...
S M, Debanne, H S, Haller
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A Nomographic Probit Solution for the Median Effective Dose (ED50)
The Journal of Immunology, 1950Summary A simple and rapid nomographic probit solution for the median effective dose (ED50) is proposed. ED50 and the slope of the dosage-response curve are directly read off from the same nomogram. Additional nomograms convert death rates into probits, and give estimates of the standard error of ED50, the standard error of the slope ...
W, KOCH, D, KAPLAN
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Background Although intrathecal ropivacaine has been widely used for caesarean delivery, there are limited data for the use of ropivacaine for prophylactic cervical cerclage. We sought to determine the median effective dose of intrathecal ropivacaine for prophylactic cervical cerclage in 50% of patients (ED50) and ...
Kun Liu +4 more
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Median Effective Doses (ED50) of Halothane in Adults and Children
Anesthesiology, 1969Median effective doses of halothane (ED50), determined in 73 pediatric subjects and 31 adults grouped according to age, were: 1.20 per cent at 0 to 6 months; 1.16 per cent at 6 to 24 months; 1.07 per cent at 24 to 48 months; and 0.9 per cent in adults. The dose-response curves for all groups did not deviate significantly from parallelism. Halothane was
H F, Nicodemus +3 more
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The Effect of Massive Doses of Neutrons on the Median Survival Time of Mice
Radiation Research, 1956The median survival time of experimental animals exposed to Xor y-ray dosages ranging from 100 to more than 100,000 r has been determined by a number of investigators (1-8). In general there is excellent agreement as to the shape of the doseresponse curve and as to the fact that this curve shows several distinct segments which may be related to ...
S M, ROTHERMEL +2 more
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