Results 241 to 250 of about 697,972 (287)

Median Effective Doses (ED50) of Halothane in Adults and Children

Anesthesiology, 1969
Median effective doses of halothane (ED50), determined in 73 pediatric subjects and 31 adults grouped according to age, were: 1.20 per cent at 0 to 6 months; 1.16 per cent at 6 to 24 months; 1.07 per cent at 24 to 48 months; and 0.9 per cent in adults. The dose-response curves for all groups did not deviate significantly from parallelism. Halothane was
H F, Nicodemus, C, Nassiri-Rahimi, L, Bachman, T C, Smith   +3 more
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Median effective dose of isoflurane, sevoflurane, and desflurane in green iguanas

American Journal of Veterinary Research, 2006
Abstract Objective—To determine the median effective dose (ED50; equivalent to the minimum alveolar concentration [MAC]) of isoflurane, sevoflurane, and desflurane for anesthesia in iguanas. Animals—6 healthy adult green iguanas. Procedure—In unmedicated iguanas, anesthesia was induced and maintained with each of the 3 volatile drugs administered on ...
Linda S, Barter, Michelle G, Hawkins, Robert J, Brosnan, Joseph F, Antognini, Bruno H, Pypendop   +4 more
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The Effect of Massive Doses of Neutrons on the Median Survival Time of Mice

Radiation Research, 1956
The median survival time of experimental animals exposed to Xor y-ray dosages ranging from 100 to more than 100,000 r has been determined by a number of investigators (1-8). In general there is excellent agreement as to the shape of the doseresponse curve and as to the fact that this curve shows several distinct segments which may be related to ...
S M, ROTHERMEL, J B, STORER, K T, WOODWARD   +2 more
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Median effective dose of propofol required for induction of anesthesia in goats

Journal of the American Veterinary Medical Association, 1997
Objective— To determine the median effective dose (ED 50 ) of propofol required for induction of anesthesia in goats and the frequency of myoclonic activity and apnea associated with propofol administration.
L S, Pablo, J E, Bailey, J C, Ko
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Interval estimation of the median effective dose for a logistic dose-response curve

Journal of Applied Statistics, 1999
In 1986, Williams showed how, assuming a logistic dose-response curve, one can construct a confidence interval for the median effective dose from the asymptotic likelihood ratio test. He gave reasons for preferring this likelihood ratio interval to the established interval calculated by applying Fieller's theorem to the maximum-likelihood estimates ...
Peter Harris, Mark Hann, Simon P. J. Kirby, John C. Dearden   +3 more
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Interpretation of confidence intervals for median effective dose estimates

Environmental Toxicology and Chemistry, 1989
Abstract Philosophical considerations in the interpretation of probability can confuse the meaning of interval estimates. Most techniques for calculating interval estimates for the median effective dose (LC50) have been developed under a Neyman-Pearson probability structure, which requires interpretation in terms of asymptotic ...
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Misuse of âDeduced Ratiosâ in the Estimation of Median Effective Doses

Nature, 1947
Dragstedt and Lang1 wrote: “It seems to us obvious that a rabbit that died from 100 mgm. would have died of any higher dose and one that survived from 150 mgm. per kilogram would have survived from any lesser dose”, and tabulated their “mortality percentages” as deduced according to “this rationale” from experienced ratios at the various doses ...
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A Comparison of Median Effective Doses of Intrathecal Levobupivacaine and Ropivacaine for Labor Analgesia

Anesthesiology, 2005
Background The study was designed to determine and compare the median effective doses (MEDs) of intrathecal ropivacaine with levobupivacaine for labor analgesia. Methods In this double-blind study, 100 parturients in early labor were randomized to receive either intrathecal ...
Alex T, Sia, Raymond W, Goy, Yvonne, Lim, Cecilia E, Ocampo   +3 more
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Optimal Bayesian estimation of the median effective dose

Journal of Statistical Planning and Inference, 1988
This paper provides some properties of the Fisher information function arising in quantal response bioassay, attribute life testing and dilution assay models. It is shown that the Fisher information function (arising in probit, logit and extreme value models) is a totally positive function of order 2 and consequently unimodal as a function of the ...
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A STUDY OF THE INDIVIDUAL MEDIAN EFFECTIVE DOSE OF OESTRONE IN THE OVARIECTOMIZED MOUSE

Journal of Endocrinology, 1955
SUMMARY Two methods of estimating the individual median effective dose have been studied and found to yield equivalent estimates. Within-animal variation (over a period of 5 weeks) is shown to be 29% (20–38%) of the between-animal variation.
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