Results 241 to 250 of about 452,355 (274)

The Effect of Age on the Median Effective Dose (ED50) of Intrathecally Administered Plain Bupivacaine for Motor Block

Anesthesia & Analgesia, 2014
In this study, we sought to determine the median effective dose (ED50) for motor block of intrathecally administered plain bupivacaine in adults (20-80 years) and to assess the effect of age on ED50 required for motor block.This study was performed in 129 adult patients undergoing transurethral, urological, or lower limb surgery under combined spinal ...
Mingquan, Chen, Chun, Chen, Qibin, Ke
openaire   +2 more sources

The Median Effective Dose of Ketamine and Gabapentin in Opioid-Induced Hyperalgesia in Rats

Anesthesia & Analgesia, 2011
Ketamine and gabapentin have been shown to prevent the delayed hyperalgesia induced by short-term use of systemic opioids. The mechanism of this action is believed to be likely at the spinal level, through an antagonism of the N-methyl-D-aspartate receptors for ketamine, and through a specific binding site for gabapentin.
Alain C, Van Elstraete, Philippe, Sitbon, Dan, Benhamou, Jean-Xavier, Mazoit   +3 more
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Specifications for Calculating. The Median Effective Dose

American Industrial Hygiene Association Quarterly, 1953
C S, WEIL, C P, CARPENTER, H F, SMYTH
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Comparison of dose-effect relationships of carcinogens following low-dose chronic exposure and high-dose single injection: an analysis by the median-effect principle

Carcinogenesis, 1980
Experimental dose-effect relationships of carcinogens following either acute (single dose) or chronic (time to tumor) exposure appears to conform with the median-effect principle (Chou, J. Theor. Biol. 59, 253-276, 1976) of the mass-action law: f(a)/ (1 - f(a)) = (D/D(m))m, where D is dose or cumulative dose, D(m) is the D required for the median ...
openaire   +2 more sources

Quantification of Toxic Response and the Development of the Median Effective Dose (Ed 50)—a Historical Perspective

Toxicology and Industrial Health, 1989
The development of the widely-used median effective (or lethal) dose as a summary measure in quantifying toxic response to chemical stimuli is reviewed. Attention is directed at those mathematical properties noted by the originator of the median effective dose, the English physiologist John William Trevan, that make the measure a useful summary ...
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Estimation of the Median Effective Dose in Bioassay

SIAM Review, 1981
openaire   +1 more source

Novel method for calculating the effective dose using size-specific dose estimates conversion factors in abdomen–pelvis computed tomography

Radiological Physics and Technology, 2023
Kentaro Funashima, Kazuhiro Sato, Sato Kazuhiro   +2 more
exaly  

Interval Estimation with Small Samples for Median Lethal Dose or Median Effective Dose

1998
openaire   +1 more source

Estimating Effective Dose for CT Using Dose–Length Product Compared With Using Organ Doses: Consequences of Adopting International Commission on Radiological Protection Publication 103 or Dual-Energy Scanning

American Journal of Roentgenology, 2010
James M Kofler, Cynthia H Mccollough
exaly  

Effective dose range for dental cone beam computed tomography scanners

European Journal of Radiology, 2012
Ruben Pauwels, Bruno Collaert, Hilde Bosmans   +2 more
exaly