Results 11 to 20 of about 4,221 (131)

Optimal lidocaine propofol mixture for painless induction of anesthesia [PDF]

open access: yesSaudi Journal of Anaesthesia
Objective: To determine the median effective dose (ED50) of 2% lidocaine mixed with propofol for preventing pain during the induction of anesthesia using a modified Dixon’s up-and-down method.
Hitham M. A. Elsayed   +3 more
doaj   +2 more sources

Effective Doses of Oliceridine Combined with Propofol for Painless Hysteroscopy: A Prospective Dose-Finding Study [PDF]

open access: yesInternational Journal of General Medicine
Liangliang Gao,1,* Aiping Tan,1,* Zehui Wang,2 Lei Wei,1 Xingshuang Wang1 1Department of Anesthesiology, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, People’s Republic of China; 2Department of Anesthesiology, Cixi ...
Gao L, Tan A, Wang Z, Wei L, Wang X
doaj   +2 more sources

Rethinking Statin Dosage in Coronary Disease. [PDF]

open access: yesPharmacol Res Perspect
It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Dimmitt SB   +3 more
europepmc   +2 more sources

Evaluation the sedative and analgesic effects of tramadol and chlorpromazine alone or as a combination in chicks

open access: yesKufa Journal for Veterinary Medical Sciences, 2021
The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in
Manahel Allawi Abdulla Aljbori   +2 more
doaj   +1 more source

Median effective dose of esketamine for intranasal premedication in children with congenital heart disease

open access: yesBMC Anesthesiology, 2023
Background Esketamine is commonly used as a premedication for its sedation effect. However, the proper dosage for intranasal use in children with congenital heart disease (CHD) has not been determined.
Jiajia Huang   +3 more
doaj   +1 more source

Dose–response study of prophylactic nitroglycerin for prevention of pituitrin-induced hypertension during laparoscopic myomectomy: a prospective, randomized study

open access: yesFrontiers in Medicine, 2023
ObjectiveTo determine the dose–response of nitroglycerin in preventing pituitrin-induced hypertension in patients undergoing laparoscopic myomectomy.MethodsHundred patients scheduled for elective laparoscopic myomectomy were randomly allocated into one ...
Jin Wang   +5 more
doaj   +1 more source

Median effective dose (ED50) of paracetamol and morphine for postoperative pain: a study of interaction [PDF]

open access: yesBritish Journal of Anaesthesia, 2014
Abstract Background Paracetamol is widely used to treat postoperative pain and is well known for its morphine-sparing effect. Therefore, the effect of morphine–paracetamol combination can be synergistic, additive, or infra-additive. The primary aim of our study is to define the median effective analgesic doses (ED50s) of paracetamol, morphine, and ...
A. Zeidan   +5 more
openaire   +1 more source

The ED50 and ED95 of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy: a prospective, double-blinded trial

open access: yesBMC Anesthesiology, 2023
Background This study aims to estimate the safety, efficacy, and median effective dose (ED50) of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy.
Zhongling Xu   +5 more
doaj   +1 more source

Long-term high-risk drinking does not change effective doses of propofol for successful insertion of gastroscope in Chinese male patients

open access: yesBMC Anesthesiology, 2022
Background Available literature indicates that long-term drinkers demand a higher dose of propofol for induction of anesthesia than non-drinkers. However, there is no study having assessed the influence of long-term high-risk drinking (LTHRD) on the ...
Pei-Pei Hao   +6 more
doaj   +1 more source

A sequential allocation study to determine the ED50 of Dexmedetomidine as an adjuvant to lidocaine intravenous regional anesthesia

open access: yesBMC Anesthesiology, 2022
Background Intravenous regional anesthesia is an easy and reliable anesthetic technique, but its use is limited by tourniquet pain. Clonidine is effective in overcoming this shortcoming when used with intravenous regional anesthesia at a dose of 1 μg/kg.
Cynthia Karam   +3 more
doaj   +1 more source

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