Results 21 to 30 of about 7,197,670 (160)

The ED50 and ED95 of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy: a prospective, double-blinded trial

BMC Anesthesiology, 2023
Background This study aims to estimate the safety, efficacy, and median effective dose (ED50) of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy.
Zhongling Xu, Yantao Lang, Xiaolei Xu, Linjuan Deng, Hengya Song, Dekun Yin   +5 more
doaj   +1 more source

Dose–response study of prophylactic nitroglycerin for prevention of pituitrin-induced hypertension during laparoscopic myomectomy: a prospective, randomized study

Frontiers in Medicine, 2023
ObjectiveTo determine the dose–response of nitroglycerin in preventing pituitrin-induced hypertension in patients undergoing laparoscopic myomectomy.MethodsHundred patients scheduled for elective laparoscopic myomectomy were randomly allocated into one ...
Jin Wang, Jin Wang, Qiang Xu, Qiang Xu, Fei Xiao, Gang Chen   +5 more
doaj   +1 more source

Long-term high-risk drinking does not change effective doses of propofol for successful insertion of gastroscope in Chinese male patients

BMC Anesthesiology, 2022
Background Available literature indicates that long-term drinkers demand a higher dose of propofol for induction of anesthesia than non-drinkers. However, there is no study having assessed the influence of long-term high-risk drinking (LTHRD) on the ...
Pei-Pei Hao, Tian Tian, Bin Hu, Wei-Chao Liu, Ying-Gui Chen, Tian-Yu Jiang, Fu-Shan Xue   +6 more
doaj   +1 more source

A sequential allocation study to determine the ED50 of Dexmedetomidine as an adjuvant to lidocaine intravenous regional anesthesia

BMC Anesthesiology, 2022
Background Intravenous regional anesthesia is an easy and reliable anesthetic technique, but its use is limited by tourniquet pain. Clonidine is effective in overcoming this shortcoming when used with intravenous regional anesthesia at a dose of 1 μg/kg.
Cynthia Karam, Sadek Al Assadi, Ghassan Kanazi, Carine Zeeni   +3 more
doaj   +1 more source

Median effective dose of intravenous nalmefene for preventing sufentanil-induced cough in children aged 1-6 years: a prospective randomized controlled trial. [PDF]

Front Pediatr
Background Sufentanil-induced cough (SIC) during anesthetic induction carries greater risks in young children than in adults owing to their limited functional residual capacity and elevated oxygen demand.
Wang C, Wang F, Li L, Wang X, Qiao L, Wang F.   +5 more
europepmc   +2 more sources

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study

EClinicalMedicine, 2022
Summary: Background: The protective immunity against omicron following a BNT162b2 Pfizer booster dose among elderly individuals (ie, those aged >65 years) is not well characterised.
Timothée Bruel, Laurie Pinaud, Laura Tondeur, Delphine Planas, Isabelle Staropoli, Françoise Porrot, Florence Guivel-Benhassine, Mikaël Attia, Stéphane Pelleau, Tom Woudenberg, Cécile Duru, Aymar Davy Koffi, Sandrine Castelain, Sandrine Fernandes-Pellerin, Nathalie Jolly, Louise Perrin De Facci, Emmanuel Roux, Marie-Noëlle Ungeheuer, Sylvie Van Der Werf, Michael White, Olivier Schwartz, Arnaud Fontanet   +21 more
doaj   +1 more source

Moderate sedation with single-dose remimazolam tosilate in elderly male patients undergoing transurethral resection of the prostate with spinal anesthesia: a prospective, single-arm, single-centre clinical trial

BMC Anesthesiology, 2022
Background Remimazolam tosilate (RT) is a newly listed benzodiazepine for sedation and anesthesia featuring quick onset of effects, short maintenance and recovery times, which is currently under research.
Tang-yuan-meng Zhao, Di Chen, Hu Sun, Zhi-xin Xu, Song Lyu, Tao Wang, Li-li Liu   +6 more
doaj   +1 more source

ED50

, 2022
The ED50 (median effective dose) is the dose of a medication that produces a specific effect in 50% of the population that takes that dose. This number has common use as what a clinician or patient can expect for a drug effect, but clinicians may use a ...
Preuss, Charles, McPhee, Arthur S., Kenny, Brian   +2 more
core   +1 more source

High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]

, 2013
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Markus Ratka, Milickovic, Natasa, Nikolaos Zamboglou, Dimos Baltas, Zamboglou, Nikolaos, Ratka, Markus, Natasa Milickovic, Chatzikonstantinou, Georgios, Tunn, Ulf W., Baltas, Dimos, Tselis, Nikolaos, Georgios Chatzikonstantinou, Nikolaos Tselis, Ulf W Tunn   +13 more
core   +1 more source

ED50 of Propofol Combined with Nalbuphine on the Sedative Effect in Painless Hysteroscopy

Pain and Therapy, 2021
Introduction Nalbuphine has gradually become a commonly used clinical analgesic drug for painless hysteroscopy. The aim of our study was to identify the median effective dose (ED50) of propofol combined with nalbuphine for painless hysteroscopy.
Chen Chen, Weixiang Tang, Wei Ye, Weiwei Zhong, Yuanhai Li   +4 more
doaj   +1 more source