Results 11 to 20 of about 7,197,670 (160)

Median effective dose of nefopam to treat postoperative pain in patients who have undergone laparoscopic cholecystectomy

Journal of International Medical Research, 2018
Objective Nefopam is thought to reduce postoperative pain; however, the evidence is insufficient. The recommended dose is 20 mg, and the median effective dose (ED50) in the surgical setting reportedly ranges from 17 to 28 mg.
Heezoo Kim, Dong Kyu Lee, Mi Kyoung Lee, Mido Lee   +3 more
doaj   +2 more sources

Determination of the Median Effective Dose of Ciprofol Combined with Sufentanil in Inhibiting Tracheal Intubation Response in Female Patients

Scientific Reports
To determine the median effective dose (ED50) and the 95% effective dose (ED95) of ciprofol combined with sufentanil for inhibiting the tracheal intubation response in female patients and to evaluate the hemodynamic stability and adverse events ...
Li Zhao, Xuelei Zhou, Ting Zhang, Wei Mao, Linlin Chen, Yiping Guo, Xianchun Liu, Longyi Zhang, Linji Li   +8 more
doaj   +2 more sources

Determination of ED50 and ED95 of remimazolam besylate combined with alfentanil for adult gastroscopy: a prospective dose-finding study

Brazilian Journal of Anesthesiology
Background: To explore the median effective dose (ED50) and 95% effective dose (ED95) of remimazolam besylate combined with alfentanil for adult gastroscopy.
Pingjuan Wang, Song Xue, Liufei Zhang, Kunkun Gao, Yiqiao Wang   +4 more
doaj   +2 more sources

The 50% and 95% effective dose of remimazolam tosilate for anaesthesia induction in sleep disorders patients undergoing laparoscopic cholecystectomy: an up-and-down sequential allocation trial

BMC Anesthesiology
Purpose Previous reports argue that preoperative sleep conditions of patients can influence the dosage of general anaesthesia drugs. Therefore, we aimed to investigate the dose-effect relationship of preoperative sleep disorders on the induction of ...
Yue Xiao, Yanan Cao, Jie Pu, Chendong Guo, Yanzi Yi, Youming Deng, Yimin Hu   +6 more
doaj   +2 more sources

ED50 of intrathecal ropivacaine for cesarean delivery with and without epidural volume extension with normal saline: a randomized controlled study.

Journal of Pain Research, 2018
M Lv,1 P Zhang,2 Z Wang3 1Department of Obestetrics and Gynecology, Affiliated Women and Children’s Hospital of Jiaxing University, Jiaxing, China; 2Department of Anesthesiology, Affiliated Women and Children’s Hospital of Jiaxing University,
Lv M, Zhang P, Wang Z
doaj   +1 more source

Effects of voltage-gated sodium channels on the median effective dose of ropivacaine in diabetic rats. [PDF]

Sci Rep
Diabetes mellitus significantly impacts perioperative anesthetic management. Patients with diabetic neuropathy exhibit increased sensitivity to local anesthetics, yet the underlying mechanisms, particularly regarding the median effective dose (ED50) of ...
Song X, Lv K, Yu P, Liu X, Yu Y, Cao G, Tai Y, Zhao B, Wang Q.   +8 more
europepmc   +2 more sources

Isobolographic Analysis of the Interaction Between Remimazolam and Etomidate in General Anesthesia Induction: A Prospective, Sequential Allocation Study Based on the Dixon Up-and-Down Method. [PDF]

Drug Des Devel Ther
Wei Yue,1,* Jiayan Huang,2,* Qi Wang,2 Furong Zheng,2 Pengfei Yin,3 Yaohua Jin,2 Yue Wang,4 Linzhong Zhang1 1College of Anesthesiology, Shanxi Medical University and Department of Anesthesiology, Second Hospital of Shanxi Medical ...
Yue W, Huang J, Wang Q, Zheng F, Yin P, Jin Y, Wang Y, Zhang L.   +7 more
europepmc   +2 more sources

Effect of Concentration on Median Effective Dose (ED50) for Motor Block of Intrathecal Plain Bupivacaine in Elderly Patients. [PDF]

Med Sci Monit, 2015
Chen MQ, Xia ZY.
europepmc   +2 more sources

Evaluation the sedative and analgesic effects of tramadol and chlorpromazine alone or as a combination in chicks

Kufa Journal for Veterinary Medical Sciences, 2021
The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in
Manahel Allawi Abdulla Aljbori, Rawnaq Faris Abdulqader Alshalchi, Ghada Abdulmunem Faris   +2 more
doaj   +1 more source

Median effective dose of esketamine for intranasal premedication in children with congenital heart disease

BMC Anesthesiology, 2023
Background Esketamine is commonly used as a premedication for its sedation effect. However, the proper dosage for intranasal use in children with congenital heart disease (CHD) has not been determined.
Jiajia Huang, Daoqing Liu, Jie Bai, Hongbin Gu   +3 more
doaj   +1 more source