Results 21 to 30 of about 4,221 (131)

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study

EClinicalMedicine, 2022
Summary: Background: The protective immunity against omicron following a BNT162b2 Pfizer booster dose among elderly individuals (ie, those aged >65 years) is not well characterised.
Timothée Bruel, Laurie Pinaud, Laura Tondeur, Delphine Planas, Isabelle Staropoli, Françoise Porrot, Florence Guivel-Benhassine, Mikaël Attia, Stéphane Pelleau, Tom Woudenberg, Cécile Duru, Aymar Davy Koffi, Sandrine Castelain, Sandrine Fernandes-Pellerin, Nathalie Jolly, Louise Perrin De Facci, Emmanuel Roux, Marie-Noëlle Ungeheuer, Sylvie Van Der Werf, Michael White, Olivier Schwartz, Arnaud Fontanet   +21 more
doaj   +1 more source

Determination of the median effective dose (ED50) of bupivacaine and ropivacaine unilateral spinal anesthesia [PDF]

Der Anaesthesist, 2017
Unilateral spinal anesthesia (USpA) has been reported to potentiate spinal anaesthesia and is used in geriatric patients. The purpose of this study was to determine the median effective dose (ED50) of 0.5% hypobaric bupivacaine and 0.5% hypobaric ropivacaine USpA for geriatric patients (age ≥ 70 years) undergoing elective hip replacement surgery.A ...
Wang, WeiBing, Li, YuanHai, Sun, AiJiao, Yu, HongPing, Dong, JingChun, Xu, Huang   +5 more
openaire   +2 more sources

A New Distribution for Modeling both Blood Cancer Data and Median Effective Dose (ED50) of Artemether-Lumefantrine against P. falciparum

Earthline Journal of Mathematical Sciences, 2023
In this paper, a novel distribution was proposed for modeling data on Leukemia and median effective dose (ED50) of Artemether-Lumefantrine against Plasmodium falciparum. Plasmodium falciparum or P. falciparum is one of the protozoan species that causes malaria.
Bright Chimezie Nwankwo, Joan Nmesoma Orjiakoh, Mmesoma P. Nwankwo, Ejiofor Innocent Mary Ifedibalu Chukwu, Okechukwu J. Obulezi   +4 more
openaire   +1 more source

Moderate sedation with single-dose remimazolam tosilate in elderly male patients undergoing transurethral resection of the prostate with spinal anesthesia: a prospective, single-arm, single-centre clinical trial

BMC Anesthesiology, 2022
Background Remimazolam tosilate (RT) is a newly listed benzodiazepine for sedation and anesthesia featuring quick onset of effects, short maintenance and recovery times, which is currently under research.
Tang-yuan-meng Zhao, Di Chen, Hu Sun, Zhi-xin Xu, Song Lyu, Tao Wang, Li-li Liu   +6 more
doaj   +1 more source

Determination of the median effective dose ( ED ₅₀ ) of spinal chloroprocaine in labour analgesia [PDF]

Anaesthesia, 2017
Summary The primary goal of this study was to determine the median effective dose ( ED 50 ) of spinal chloroprocaine for labour analgesia. Thirty‐eight parturients requesting neuraxial analgesia were enrolled. Doses of 1% chloroprocaine were determined by
M, Coppens, S, Anssens, A, Parashchanka, K, Roelens, E, Deschepper, S, De Hert, P F, Wouters   +6 more
openaire   +2 more sources

ED50 of Propofol Combined with Nalbuphine on the Sedative Effect in Painless Hysteroscopy

Pain and Therapy, 2021
Introduction Nalbuphine has gradually become a commonly used clinical analgesic drug for painless hysteroscopy. The aim of our study was to identify the median effective dose (ED50) of propofol combined with nalbuphine for painless hysteroscopy.
Chen Chen, Weixiang Tang, Wei Ye, Weiwei Zhong, Yuanhai Li   +4 more
doaj   +1 more source

Median effective doses (ED50) of halothane and chloroform in sensitive and resistant strains of Drosophila melanogaster.

The Japanese Journal of Genetics, 1980
Ether resistant strain (Eth-29) and one of the sensitive strains (bw; st; svn) which were assessed by mortalities, were used to determine median effective doses (ED50) of halothane and chloroform. It was demonstrated that the Eth-29 strain was resistant and the bw; st; svn strain was sensitive to both of halothane and chloroform anesthesia.
SUMIKO GAMO, EIJI NAKASHIMA-TANAKA, MASAHIRO OGAKI   +2 more
openaire   +2 more sources

Effective Doses of Nalbuphine Combined with Propofol in Painless Hysteroscopy

International Journal of General Medicine, 2022
Weiwei Zhong,* Chen Chen,* Weixiang Tang Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China*These authors contributed equally to this workCorrespondence ...
Zhong W, Chen C, Tang W
doaj  

Median effective dose of nefopam to treat postoperative pain in patients who have undergone laparoscopic cholecystectomy

Journal of International Medical Research, 2018
Objective Nefopam is thought to reduce postoperative pain; however, the evidence is insufficient. The recommended dose is 20 mg, and the median effective dose (ED50) in the surgical setting reportedly ranges from 17 to 28 mg.
Heezoo Kim, Dong Kyu Lee, Mi Kyoung Lee, Mido Lee   +3 more
doaj   +1 more source

Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for ED50 determination using an up-down sequential allocation method

BMC Anesthesiology, 2023
Background Intrathecal dexmedetomidine, as an adjuvant to local anesthetics, has been reported to improve the quality of spinal anesthesia and reduce the required local anesthetic dose.
Xiaofei Mo, Fa Huang, Xiaoying Wu, Jumian Feng, Jiequn Zeng, Jinghui Chen   +5 more
doaj   +1 more source