Results 51 to 60 of about 4,221 (131)

Synergistic Effect of Combination Treatment of Brexpiprazole and Nalmefene on Ethanol Intake in Rats

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Combination effect of nalmefene and brexpiprazole on ethanol intake in rats. The combination of subeffective doses of nalmefene (0.04 mg/kg, s.c.) and brexpiprazole (0.01 mg/kg, p.o.) significantly and synergistically decreased the average ethanol intake for 4 days compared with before the treatment (interaction effect: p = 0.0033 by two‐way ANOVA ...
Naoki Amada, Mai Nakamura, Yuta Ohgi, Yusuke Kakumoto, Mikio Suzuki, Takashi Futamura, Kenji Maeda   +6 more
wiley   +1 more source

Additional file 1 of The median effective dose (ED50) of cis-Atracurium for laryngeal mask airway insertion during general Anaesthesia for patients undergoing urinary surgery

, 2020
Additional file 1: Table S1. Findings Regarding Resistance to Mouth Opening, Resistance to Insertion, Cough, Swallowing, Laryngospasm/Airway Obstruction, and Head and Body Movement.
Wang, Xiaohua, Huang, Ke, Yan, Hao, Lan, Fei, Yao, Dongxu, Li, Yanhong, Xue, Jixiu, Wang, Tianlong   +7 more
openaire   +1 more source

Comparison of Uptake of Cadmium at Low Concentrations Under Hydroponic and Soil‐Based Agriculture Systems for Lettuce, Indian Spinach and Methi

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
ABSTRACT Using recycled water for agriculture offers a sustainable approach by adding inherent nutrients and moisture to the soil. However, it contains unwanted contaminants such as heavy metals like cadmium at lower concentrations. This study assessed the comparative response of three leafy crops ‐ lettuce, Indian spinach and methi, against cadmium ...
Devishetty Jayadevappa Kotresh, Hadiveppa Marulappa Jayadeva, Dharmappa Hagare, Gundappa Guruputrappa Kadalli, Basant Maheshwari, Benherlal Palayyan Saraswathy, Vishwanath Krishnappa, Pruthviraj Narasimhamurthy, Mahantesh Basangouda Nagangoudar, Vinay Mallikarjuna Gangana Gowdra, Mummasani Asritha, Santosh Araganji, Sonu Sonu   +12 more
wiley   +1 more source

Anesthesia Practices for Preterm Infants: A Survey in the Nordic Countries and Review of the Literature

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Preterm infants are at increased risk of perioperative mortality and are among the most vulnerable patients anesthesiologists can encounter. The literature on anesthesia practice in preterm infants is limited, mainly focusing on their physiological immaturity and related pharmacodynamics and pharmacokinetics.
Jaap van der Heijden, Peter Frykholm
wiley   +1 more source

Determination of ED50 and time to effectiveness for intrathecal hydromorphone in laboring patients using Dixon’s up-and-down sequential allocation method

BMC Anesthesiology, 2018
Background With the increasing occurrence of drug shortages, understanding the pharmacokinetics of alternative intrathecal opioid administration has gained importance.
Vikas O’Reilly-Shah, Grant C Lynde
doaj   +1 more source

Therapeutic Activities and Phytochemical Composition of Helianthus annuus L. Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The sunflower (Helianthus annuus L.) is a plant commonly used in agriculture and the fuel industry, as well as being an ornamental garden plant. However, its biologically active compounds make it an interesting plant for medicinal purposes. This review evaluated the phytochemistry of sunflower leaves, stems, receptacles, flowers, seeds, and ...
Marina dos Santos Barreto, Wesley Lisboa de Jesus, Maria Eduarda de Britto Sá, Jessiane Bispo de Souza, Ronaldy Santana Santos, Júlia Santana Lisboa, Pedro Henrique Macedo Moura, Deise Maria Rego Rodrigues Silva, Eloia Emanuelly Dias Silva, Lysandro Pinto Borges, Adriana Gibara Guimarães   +10 more
wiley   +1 more source

Optimizing nicardipine dosage for effective control of pituitrin-induced hypertension in laparoscopic myomectomy undergoing total intravenous anesthesia

BMC Anesthesiology
Background This study aimed to determine the median effective dose (ED50) and 95% effective dose (ED95) of nicardipine for treating pituitrin-induced hypertension during laparoscopic myomectomy, providing guidance for the management of intraoperative ...
Chen Wang, Xiaoli Zhao, Yunyun Chen, Jianhua Xia, Xixue Zhang, Tingting Wang   +5 more
doaj   +1 more source

The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients

Clinical &Translational Immunology, Volume 15, Issue 2, 2026.
We characterised B‐cell responses to vaccination in allogeneic haematopoietic stem cell transplant (alloHCT) recipients. While mRNA prime‐boost vaccination stimulated expansion of vaccine‐specific B cells to affinity mature in a majority of alloHCT recipients, responses were variable and seemingly restricted by the presence of immature B‐cell ...
Fredrika Hellgren, Rodrigo Arcoverde Cerveira, Gustaf Lindgren, Puran Chen, Klara Lenart, Sebastian Ols, Alberto Cagigi, Davide Valentini, Mireia Rocavert Barranco, Evangelin Shaloom Vitus, Martin Corcoran, Yong‐Dae Gwon, Mattias NE Forsell, Magnus Evander, COVAXID Study Group, Peter Bergman, Marcus Buggert, Hans‐Gustaf Ljunggren, Soo Aleman, Gunilla B Karlsson Hedestam, Andreas Björklund, Anna Nordlander, Per Ljungman, Stephan Mielke, Karin Loré   +24 more
wiley   +1 more source

Blood‐Based Lead Biomarkers and Sarcopenia Indicators in Older Adults

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Chronic exposure to low levels of lead (Pb) remains a widespread public health issue, especially among older adults. While its neurotoxic and cardiovascular effects are well recognized, its potential role in accelerating age‐related musculoskeletal decline is less understood.
Aida Koni, Alvaro Santos‐Cuerva, Mercedes Sotos‐Prieto, Rosario Ortolá, Pablo Olmedo, Javier García‐Pérez, Rebeca Ramis, Adrián Carballo‐Casla, Fernando Gil, Javier González‐Palacios, Roberto Pastor‐Barriuso, Ana Navas‐Acién, Elena Plans‐Beriso, Pablo Fernández‐Navarro, Fernando Rodríguez‐Artalejo, Esther García‐Esquinas   +15 more
wiley   +1 more source

Determination of ED50 and ED95 of remimazolam besylate combined with alfentanil for adult gastroscopy: a prospective dose-finding study

Brazilian Journal of Anesthesiology
Background: To explore the median effective dose (ED50) and 95% effective dose (ED95) of remimazolam besylate combined with alfentanil for adult gastroscopy.
Pingjuan Wang, Song Xue, Liufei Zhang, Kunkun Gao, Yiqiao Wang   +4 more
doaj   +1 more source