Results 181 to 190 of about 59,578 (214)

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Acute and Subacute Oral Toxicity Evaluation of <i>Baccaurea motleyana</i> Fruit Extract in Wistar Rats. [PDF]

Food Sci Nutr
Hasan MM, Bhuyan EA, Ekram MEH, Proma NM, Hossain MK.   +4 more
europepmc   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Nanoencapsulation of <i>Helichrysum italicum</i> (Roth) G. Don essential oil for eco-friendly control of citrus aphid (<i>Aphis spiraecola</i>). [PDF]

Front Plant Sci
Bourenane EK, Amokrane D, Bouras D, Wu X, Mohammedi A, Fellah M, Andreasen C.   +6 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Screening and Comparative Efficacy of Indigenous Entomopathogenic Fungi from Forest Ecosystems Against <i>Culex pipiens</i> Biotype <i>molestus</i> Larvae: Identification of High-Virulence Isolates for Biocontrol Applications. [PDF]

Insects
Mantzoukas S, Zarmakoupi C, Lagogiannis I, Eliopoulos PA.   +3 more
europepmc   +1 more source

A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality

Hoglund RM, Kobylinski KC, Jittamala P, Hanboonkunupakarn B, Wamaket N, Sriwichai P, Phasomkusolsil S, White NJ, Day NP, Tarning J.   +9 more
europepmc   +1 more source

A mouse-adapted Yezo virus model for antiviral testing in immunocompetent mice. [PDF]

Nat Commun
Xu W, Wang Y, Pan M, Tan Q, Jin F, Sui L, Zhao Y, Liu N, Liu Q.   +8 more
europepmc   +1 more source

Paralysis efficiency (PD₅₀) scales linearly with lethality (LD₅₀) in spider venoms. [PDF]

Toxicon X
Lyons K, Leonard D, McSharry L, Martindale M, Collier BL, Vitkauskaite A, Dunbar JP, Dugon MM, Healy K.   +8 more
europepmc   +1 more source