Results 211 to 220 of about 56,603 (238)

Estimation of Median Lethal Dose of Cypermethrin and Betacyfluthrin

INTERNATIONAL JOURNAL OF TOXICOLOGICAL AND PHARMACOLOGICAL RESEARCH, 2017
Present study was aimed to evaluate the median lethal dose (LD50) of two broadly used, type II pyrethroid pesticides Cypermethrin and Beta-cyfluthrin against Wistar albino rats. The albino rats corresponding to experimental sets were orally administrated different doses of selected pyrethroids for estimation of median lethal dose.
Brijender Bhushan, Prabhu Narain Saxena
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Approximate lethal dose versus median lethal dose in acute toxicity testing of pharmaceuticals

Archives of Toxicology, 1989
The relation between approximate lethal doses (ALD, i.e. the lowest dose at which mortality occurs) and the corresponding median lethal doses (LD50) was investigated in 231 acute toxicity studies in mice and rats. The ALD values were divided into four classes (less than 5 mg/kg, 5-50 mg/kg, 50-500 mg/kg, 500-2000 mg/kg) and the LD50/ALD factors were ...
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Median Lethal Dose for Guinea Pigs of Cobalt-60 Gamma Irradiation

Radiation Research, 1960
The acute 30-day median lethal dose in Hartley guinea pigs was determined for cobalt-60 gamma -irradiation. The median lethal dose was found to be 326 rads, Change in weight of the irradiated animals was recorded for a period of 30 days. Extravasation of blood into viscera and serous cavities was the most frequent finding at autopsy. (auth)
W T, NEWTON, M, TER-POGOSSIAN
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The Median Lethal Dose-Design and Estimation

Journal of the Royal Statistical Society: Series D (The Statistician), 2001
Summary. A biological assay from a pharmaceutical company is simulated with various designs and a range of parameter values. Three estimation techniques-Fieller's method, profile likelihood and the bootstrap-of finding confidence intervals for the median lethal dose LD50 are compared.
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Corrigendum: The Median Lethal Dose-Design and Estimation

Journal of the Royal Statistical Society: Series D (The Statistician), 2001
I am grateful to Graham Healey, Huntingdon Life Sciences Limited, and Jochen Mueller-Cohrs, Aventis Behring GmbH, Marburg, for pointing out the following error. Owing to a computing error in calculating the deviance the results on the likelihood ratio (LR) method in Table 1 were incorrect. It has now been recomputed and is shown below. Section 4 should
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Estimation of the Median Lethal Dose When Responses within a Litter are Correlated

Biometrics, 1981
In the analysis of mortality experiments on neonatal animals, the presence of litter effects may prevent the use of probit analysis. This communication presents a method for estimating the median lethal dose, based on a modification of the beta-binomial distribution.
A C, Segreti, A E, Munson
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Efficient Design for Estimation of Median Lethal Dose and Quantal Dose- Response Curves

Biometrics, 1990
The results of quantal dose-response experiments are often summarized by an estimate of the "median lethal dose," denoted LD50, and many sequential designs have been proposed for efficient estimation of LD50. These designs strive to produce a sequence of trials at dose levels that get closer and closer to LD50.
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[Comparison of the decurarizing and median lethal doses of 2-aminopyridine salts].

Eksperimentalna meditsina i morfologiia, 1979
The authors determined LD50 of 2-aminopyridine hydrochloride, 2-aminopyridine jodmethylate, 2-aminopyridine methyl-para-toluolsulfonat and pymadine (4-aminopyridine hydrochloride) in mice and rats after subcutaneous administration. They found that doses of the same compounds during indirect stimulation of m.
V, Spasov, D, Getova, A, Spasov
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Measurement of median lethal dose as a rapid indication of contaminant toxicity to fish

Environmental Toxicology and Chemistry, 1984
Abstract A new method was developed to rapidly measure the toxicity of contaminants to fish over 96 h. The method is the measurement of median lethal doses by intraperitoneal injection (IP-LD50). Contaminants are dissolved in 5% ethanol in saline or in cod-liver oil and injected at a rate of 1.0 ml per 100 g of fish.
P. V. Hodson, D. G. Dixon, K. L. E. Kaiser   +2 more
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Determination of the Median Lethal Dose of Botulinum Serotype E in Channel Catfish Fingerlings

Journal of Aquatic Animal Health, 2012
Abstract The median lethal dose of botulinum serotype E in 5.3-g channel catfish Ictalurus punctatus fingerlings was determined. Five tanks (five fish/tank) were assigned to each of the following treatment groups: 70, 50, 35, 25, or 15 pg of purified botulinum serotype E.
Kamalakar, Chatla, Patricia S, Gaunt, Larry, Hanson, Dana X, Gao, Robert, Wills   +4 more
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