Results 221 to 230 of about 112,587 (303)

[Rapid method for determining the median lethal doses of chemical substances].

Gigiena i sanitariia, 1985
T V, Pastushenko, L B, Marushiĭ, A A, Zhukov, Iu A, Pilipenko   +3 more
openaire   +1 more source

Survival Outcomes of Gemcitabine–Cisplatin–S‐1 Versus Gemcitabine–Cisplatin in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Study With a Focus on Conversion Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka, Masahiko Kinoshita, Satoshi Yasuda, Satoru Kakizaki, Rie Sugimoto, Jun Sakata, Kiyonori Yamai, Takeshi Hatanaka, Yusuke Yamamoto, Toshifumi Sato, Toru Ishikawa, Takanori Morikawa, Jun Hanaoka, Haruki Mori, Hidenori Toyoda, Tsuyoshi Sanuki, Misaki Yokoi, Hiroyuki Shibata, Koji Fukuda, Kazuhito Kawata, Koji Amaya, Takashi Ito, Masaaki Hidaka, Atsushi Naganuma, Keishi Sugimachi, Satoshi Toshiyama, Makoto Yamasaki, Masaki Kaibori   +27 more
wiley   +1 more source

A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality

Hoglund RM, Kobylinski KC, Jittamala P, Hanboonkunupakarn B, Wamaket N, Sriwichai P, Phasomkusolsil S, White NJ, Day NP, Tarning J.   +9 more
europepmc   +1 more source

Oral VV261 administration protects mice from lethal Crimean-Congo hemorrhagic fever virus challenge. [PDF]

J Virol
Wang X, Xu H, Li L, Wu F, Li J, Shen J, Xiao G, Zheng W, Zhang L, Hu Z, Wang M.   +10 more
europepmc   +1 more source

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Malathion-induced hematotoxicity, hepatotoxicity, and nephrotoxicity in male chicks. [PDF]

Front Vet Sci
Fadlalla IMT, Ali KM, Aljack BH, Atta M.
europepmc   +1 more source

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang, Tian Li, Weiran Jia, Dingjie Xu, Liangdan Sun, Yanlei Ge, Yiwei Shi, Hong Xu, Xudong Song, Fuyu Jin, Na Mao   +10 more
wiley   +1 more source

Exploration of refined humane endpoints for melioidosis in BALB/c mice. [PDF]

Lab Anim (NY)
Harris MP, Barnes KB, Laws TR, May E, Nelson M, Harding SV, Maishman TC.   +6 more
europepmc   +1 more source

Nanostructured Lipid Carriers Overcome the Low Immunogenicity of M2e Peptide via Surface Click Chemistry Conjugation, Improving the Anti‐M2e Antibody Response

Advanced NanoBiomed Research, EarlyView.
1) Nanostructured lipid carriers efficiently vectorize low‐immunogenic M2e peptide. 2) M2e peptide conjugation via click chemistry preserves the peptide key epitopes. 3) Forty M2e peptides per nanoparticle are sufficient to induce robust immune responses.
Louis Bourlon, Carole Fournier, Antoine Hoang, Christine Charrat, Alban Lepetitcolin, Jessica Morlieras, Fabrice Navarro, Patrice N. Marche   +7 more
wiley   +1 more source

Pathogenicity of a novel orthonairovirus, Iwanai Valley virus, in mice. [PDF]

J Vet Med Sci
Nishino A, Park ES, Inoue Y, Tatemoto K, Uda A, Matsumura R, Kobayashi D, Isawa H, Kasai S, Maeda K.   +9 more
europepmc   +1 more source