Results 241 to 250 of about 112,587 (303)

Isolation and identification of Aeromonas salmonicida of bovine origin and its genome-wide and pathogenicity analysis. [PDF]

Front Microbiol
Wang Q, Dong X, Cui M, Liang X, Sun Y, Chen S, Feng S, Zheng X, Liu Y.   +8 more
europepmc   +1 more source

Identification of Histone Deacetylase Inhibitor Targeting Type I Interferon and B Cell Abnormalities in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

The Genetic Architecture of Venom Resistance: A Novel Approach to Target Identification and Coevolutionary Discovery. [PDF]

Mol Biol Evol
Ward MJ, Ellsworth SA, King EG, Ng'oma E, Nystrom GS, Lawrence KC, Maquet-Diafouka L, Oliver A, Margres MJ, Parkinson CL, Hughes KA, Rokyta DR.   +11 more
europepmc   +1 more source

Tissue Damage in Rheumatoid Arthritis is Genetically linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

Arthritis &Rheumatology, Accepted Article.
Objectives Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biological mechanism underlying this association. Methods Expression of surrounding genes was compared between rs26232 genotypes.
Kevin J. Sheridan, Emma R. Dorris, Maria Inês Pimenta, Jemma Falkov, Matthew Fisher, Sam Pledger, Hector Devey, Munitta Muthana, Denis C. Shields, Richard E Mains, Betty A Eipper, Christopher D. Buckley, Anthony G. Wilson   +12 more
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non-Pharmacological Interventions to Prevent Opioid-Induced Cardiac Arrest. [PDF]

Clin Pharmacol Ther
Thrasher B, Mann J, Chaturbedi A, Chakravartula S, Meshkin H, Affan A, Galluppi A, Kim JY, Karimli N, Han Y, Dezman Z, Florian J, Li Z.   +12 more
europepmc   +1 more source

Regorafenib in refractory gastric cancer: modest median, meaningful milestone. [PDF]

J Gastrointest Oncol
Narita Y, Muro K.
europepmc   +1 more source

In vivo antiparasitic activity of biogenic Iron nanoparticles on ectoparasitic branchiuran, Argulus siamensis in Labeo rohita and effect on parasite ion channel genes. [PDF]

BMC Vet Res
Brahmchari RK, Kumari P, Kumar S, Prasad KP, Srivastava PP, Bedekar MK, Raman RP.   +6 more
europepmc   +1 more source

Characterization of <i>Hottentotta judaicus</i> Scorpion Venom: Toxic Effects and Neurobehavioral Modulation in Insect Models. [PDF]

Toxins (Basel)
Wehbe R, Karaki A, Dassouki Z, Rima M, Borges A, Roufayel R, Legros C, Fajloun Z, Kambris Z.   +8 more
europepmc   +1 more source

SARS-CoV-2 and Influenza Co-Circulation and Co-Vaccination: A Narrative Review. [PDF]

Vaccines (Basel)
Kamransarkandi M, Varyushina EA, Gorshkov AN, Stukova MA.   +3 more
europepmc   +1 more source