Results 101 to 110 of about 792,576 (296)

Singlet-Stabilized Minimal Gauge Mediation

, 2011
We propose Singlet Stabilized Minimal Gauge Mediation as a simple ISS-based model of Direct Gauge Mediation which avoids both light gauginos and Landau poles. The hidden sector is a massive s-confining SQCD that is distinguished by a minimal SU(5) flavor
Curtin, David, Tsai, Yuhsin
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The causal nexus between diverse smoking statuses, potential therapeutic targets, and NSCLC: insights from Mendelian randomization and mediation analysis

Frontiers in Oncology
ObjectiveLung cancer, the most prevalent malignancy, is typically diagnosed at an advanced stage. Smoking is a pivotal risk factor for NSCLC, yet the impact of various smoking statuses on NSCLC remains unclear.
Zhenghua Cao, Shengkun Zhao, Tong Wu, Huan Ding, Zhiyu Tian, Feng Sun, Zhuo Feng, Shaodan Hu, Li Shi   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The association of plasma asprosin with anthropometric and metabolic parameters in Korean children and adolescents

Frontiers in Endocrinology
BackgroundThis study aimed to determine the correlation of plasma asprosin with anthropometric and metabolic parameters in Korean children and adolescents.MethodsThis single-center study included 109 Korean children and adolescents: 62 (56.9%) obese ...
Shin-Hee Kim, Sung Eun Kim, Yoon Hong Chun   +2 more
doaj   +1 more source

Sense of coherence as a mediator between perceived neighborhood characteristics and health [PDF]

We examine how sense of coherence (SOC) mediates the association between perceived neighborhood characteristics and health, using micro data collected from a nationwide Internet survey in Japan conducted in 2011 (N = 9,940).
Oshio, Takashi, Urakawa, Kunio
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A follow-up empirical analysis of Scottish construction clients' interaction with mediation [PDF]

, 2013
Although across many jurisdictions, mediation’s origins (in the modern sense at least1) often lay in the dispute areas of family and community matters, in recent years the process has begun to take root in the arena of construction disputes (for an ...
Agapiou, Andrew, Clark, Bryan
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Mediating Role of Patience in the Relationship Between Coping Styles and Resilience

Anadolu Üniversitesi Eğitim Fakültesi dergisi
TThe aim of the present study was to examine the mediation effect of patience in the relationship between coping styles and resilience in university students. The sample comprised 401 university students (290 females [72.3%] and 111 males [27.7%]).
Özlem Çakmak Tolan, Muhammed Sevilgen
doaj   +1 more source