Results 121 to 130 of about 800,077 (295)

Gravitino Dark Matter in Tree Level Gauge Mediation with and without R-parity

open access: yes, 2011
We investigate the cosmological aspects of Tree Level Gauge Mediation, a recently proposed mechanism in which the breaking of supersymmetry is communicated to the soft scalar masses by extra gauge interactions at the tree level.
A Abdo   +52 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Mediating Role of Patience in the Relationship Between Coping Styles and Resilience

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi
TThe aim of the present study was to examine the mediation effect of patience in the relationship between coping styles and resilience in university students. The sample comprised 401 university students (290 females [72.3%] and 111 males [27.7%]).
Özlem Çakmak Tolan, Muhammed Sevilgen
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Association between vitamin D levels and preserved ratio impaired spirometry: an investigation of mediating roles of systemic inflammation and metabolic indicators

open access: yesFrontiers in Nutrition
BackgroundPreserved ratio impaired spirometry (PRISm) represents an abnormal lung function state distinct from traditional chronic obstructive pulmonary disease, characterized by unique clinical and epidemiological features.
Tong Lin   +4 more
doaj   +1 more source

A new approach for within-subject mediation analysis in AB/BA crossover designs [PDF]

open access: yes, 2013
Crossover trials are widely used in psychological and medical research to assess the effect of reversible exposures. In such designs, each subject is randomly allocated to a sequence of conditions, enabling the evaluation of treatment differences within ...
Josephy, Haeike   +2 more
core  

TeV scale mirage mediation in NMSSM

open access: yes, 2012
We study the next-to-minimal supersymmetric standard model. We consider soft supersymmetry breaking parameters, which are induced by the mirage mediation mechanism of supersymmetry breaking.
A Falkowski   +52 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of fear of coronavirus disease 2019 on attention-deficit/hyperactivity disorder traits associated with depressive symptoms, functional impairment, and low self-esteem in university students: a cross-sectional study with mediation analysis

open access: yesEnvironmental Health and Preventive Medicine
Background: High levels of attention-deficit/hyperactivity disorder (ADHD) traits are associated with various outcomes, including depressive symptoms, functional impairment, and low self-esteem.
Tomoko Suzuki   +5 more
doaj   +1 more source

Do psychobiosocial states mediate the relationship between perceived motivational climate and individual motivation in youngsters? [PDF]

open access: yes
Grounded in achievement goal theory and self-determination theory, this cross-sectional study examined the relationship between perceived motivational climate and individuals’ motivation as well as the mediation effect of psychobiosocial states as ...
Bertollo, Maurizio   +3 more
core  

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