Results 111 to 120 of about 23,448,155 (300)
Frontiers in Cardiovascular MedicineBackgroundThe rising incidence of cardiovascular diseases (CVD) in the elderly highlights the need for effective preventive strategies. Recent studies suggest that obesity, through metabolic factors, contributes to the development of CVD. This study aims
Kangming Li +7 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Developing the conversation about workplace mediation. [PDF]
, 2014 This article examines some of the latest writing and research in relation to conflict in work and workplace mediation. It considers three specific issues of size and sector of organisations, the attitude of organisations to conflict and the employee ...
Kenny, Treasa
core +1 more source
Egyptian Journal of Medical Human GeneticsObjective To investigate whether succinylation-related genes participate in irritable bowel syndrome (IBS) pathogenesis by regulating blood metabolites.
Lian Mo +7 more
doaj +1 more source
Frontiers in MedicineBackgroundChronic obstructive pulmonary disease (COPD) is a major contributor to early mortality, high overall mortality rates, and significant healthcare costs. Based on the Life’s Essential 8 (LE8), Life’s Crucial 9 (LC9) is a new cardiovascular health
Ziming Wang, Xinyun Xie, Hongyang Gong
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An analysis of local solicitors’ attitudes to and use of mediation [PDF]
, 2014 Legal practitioners are considered to be the “gate-keepers” for a significant proportion of the mediation work currently being undertaken in the UK. This small-scale study undertaken in Canterbury explores the attitudes of local legal practitioners to ...
Howland, A., Waters, B.
core
Understanding biodiversity effects on trophic interactions with a robust approach to path analysis
Cell Reports SustainabilitySummary: With its facility to assess causal mechanisms among multiple variables, the application of path analysis in medical, natural, and social sciences has become widespread.
Yu-Quan Wang +5 more
doaj +1 more source
THE LINK BETWEEN HUMAN DEVELOPMENT AND TAX COMPLIANCE: EVIDENCE FROM A MEDIATION ANALYSIS [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015 By performing mediation analysis with the state-of-the-art bootstrapping technique (95% bias-corrected and accelerated confidence interval; 5000 bootstrap resamples) on a worldwide sample pool of countries and territories, it is shown that human ...
BǍTRÂNCEA LARISSA
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source