Results 111 to 120 of about 4,503,991 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Medical Professionalism Development of Oliver R. Avison [PDF]
, 2009 Purpose: How does professionalism develop while becoming a great doctor? This study based on the life of Avison, a great doctor, aims to identify the developmental features of an excellence and professionally ethical doctor.
류숙희, 양은배
core
Student Research Programs in U.S. Medical Schools and Institutions
, 2015 The majority of medical educators agree that scientific education is critical to the development of physician-scientists. However, the proportion of physicians interested or engaged in research has been decreasing.
연세대학교 의과대학
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Formação e seleção de docentes para currículos inovadores na graduação em saúde
Revista Brasileira de Educação MédicaA expansão do número de vagas no ensino superior, especialmente na área da saúde, deu-se principalmente às custas do setor privado e sob as recomendações das Diretrizes Curriculares Nacionais.
José Lúcio Martins Machado +2 more
doaj +1 more source
Developments in ultrasound—Non-medical
Progress in Biophysics and Molecular Biology, 2007 Ultrasound is defined as sound of a frequency that is too high for the human ear to detect--i.e. it is inaudible. Nevertheless this "silent sound" has a large range of applications in science, medicine and industry. The study of the effects of ultrasound on materials--known as sonochemistry--is one of the broadest and most exciting areas in current ...
openaire +2 more sources
Integrating medical simulation programs into the Turkish undergraduate medical curriculum
Advances in Medical Education and Practice, 2016 Dilek Kitapçıoğlu, Mehmet Emin Aksoy Medical Education Department, Faculty of Medicine, Acibadem University, CASE - Center of Advanced Simulation and Education, Istanbul, TurkeyThe letter by Ah-kee and Khan1 arguing that a mandatory year for ...
Kitapçıoğlu D, Aksoy ME
doaj
Development of Medical Technology in Emergency Medical Services [PDF]
Prehospital and Disaster Medicine, 1992 V G, Teriaev +3 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source