Results 121 to 130 of about 4,503,991 (311)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Formação ética e humana no curso de medicina da UFRN: uma análise crítica

open access: yesRevista Brasileira de Educação Médica
Trata-se de um estudo documental, transversal, de caráter exploratório descritivo. Foram examinadas informações sobre programas e ementas referentes aos componentes curriculares obrigatórios, a fim de se proceder a uma análise crítica acerca de como o ...
Karla Patrícia Cardoso Amorim   +1 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Basic essential education program (BEEP): a brief introductory faculty development course for medical teachers

open access: yesCanadian Medical Education Journal, 2012
Background: Physicians have a unique role in teaching future physicians and allied health professionals. Yet, most medical doctors have limited instruction in this critical component of their daily activity. Methods: This study was a prospective cohort
Robert Madan   +4 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A look into medical innovations & medical devices in 2013-2017

open access: yes, 2018
Introduction: Medical innovation has led to discoveries on how to prevent and cure many illnesses. As a result, millions of people have lived longer, healthier, and more productively.
Zhelyazkova, Desislava; Faculty of Medicine, Medical University of Varna   +3 more
core   +1 more source

Development of the Medical Intensive Care Unit Shift Report Communication Scale as a measure of nurses' perception of communication

open access: yesNursing: Research and Reviews, 2013
David James,1 Angela Jukkala,2 Andres Azuero,2 Pamela Autrey,3 Lynne Vining,4 Rebecca Miltner2 1Center for Nursing Excellence, University of Alabama at Birmingham Hospital, 2School of Nursing, University of Alabama at Birmingham, 3Nursing Administration,
James D   +5 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

e‐Portfolios for Learning and Assessment in Medical Education

open access: yes, 2014
Portfolios have gained attention in medical education as a tool for promoting student learning and assessment since Miller’s call for better tools for assessing students’ clinical competencies.
연세대학교 의과대학
core  

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