Results 131 to 140 of about 2,823,528 (278)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Retracted: Quality Control in the Clinical Medical Laboratory Based on Mobile Medical Edge Computing. [PDF]

Contrast Media Mol Imaging, 2023
Imaging CMM.
europepmc   +1 more source

Medical Laboratory Haematology [PDF]

Journal of Clinical Pathology, 1991
openaire   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Medical laboratory statistics [PDF]

Journal of Immunological Methods, 1982
openaire   +2 more sources

Medical laboratory data-based models: opportunities, obstacles, and solutions. [PDF]

J Transl Med
Meng J, Wu M, Shi F, Xie Y, Wang H, Guo Y.   +5 more
europepmc   +1 more source

Continuing professional development (CPD) training needs assessment for medical laboratory professionals in Ethiopia. [PDF]

Hum Resour Health, 2023
Gebregzabher EH, Tesfaye F, Cheneke W, Negesso AE, Kedida G.   +4 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Factors associated with COVID-19 vaccine acceptance among medical laboratory workers in South Africa. [PDF]

J Public Health Afr
Motlhale M, Wilson K, Jones D, Chin G, Naicker N.   +4 more
europepmc   +1 more source

Competency for Japanese novice medical laboratory scientists: a Delphi method. [PDF]

BMC Med Educ, 2022
Maekawa K, Kotera S, Ohsaki H.
europepmc   +1 more source