Results 1 to 10 of about 575,236 (196)

Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms

iScience, 2022
Summary: We compared three hospitalized patient cohorts and conducted mechanistic studies to determine if lipotoxicity worsens COVID-19. Cohort-1 (n = 30) compared COVID-19 patients dismissed home to those requiring intensive-care unit (ICU) transfer ...
Rodrigo Cartin-Ceba, Biswajit Khatua, Bara El-Kurdi, Shubham Trivedi, Sergiy Kostenko, Zaid Imam, Ryan Smith, Christine Snozek, Sarah Navina, Vijeta Sharma, Bryce McFayden, Filip Ionescu, Eugene Stolow, Sylvia Keiser, Aziz Tejani, Allison Harrington, Phillip Acosta, Saatchi Kuwelker, Juan Echavarria, Girish B. Nair, Adam Bataineh, Vijay P. Singh   +21 more
doaj   +1 more source

Microwell-enhanced optical rapid antibiotic susceptibility testing of single bacteria

iScience, 2023
Summary: Bacteria that are resistant to antibiotics present an increasing burden on healthcare. To address this emerging crisis, novel rapid antibiotic susceptibility testing (AST) methods are eagerly needed.
Ireneusz Rosłon, Aleksandre Japaridze, Stef Rodenhuis, Lieke Hamoen, Murali Krishna Ghatkesar, Peter Steeneken, Cees Dekker, Farbod Alijani   +7 more
doaj   +1 more source

Daunorubicin resensitizes Gram-negative superbugs to the last-line antibiotics and prevents the transmission of antibiotic resistance

iScience, 2023
Summary: Although meropenem, colistin, and tigecycline are recognized as the last-line antibiotics for multidrug-resistant Gram-negative bacteria (MDR-GN), the emergence of mobile resistance genes such as blaNDM, mcr, and tet(X) severely compromises ...
Jinju Cai, Tian Deng, Jingru Shi, Chen Chen, Zhiqiang Wang, Yuan Liu   +5 more
doaj   +1 more source

An Automated Dashboard to Improve Laboratory COVID-19 Diagnostics Management

Frontiers in Digital Health, 2021
Background: In response to the COVID-19 pandemic, our microbial diagnostic laboratory located in a university hospital has implemented several distinct SARS-CoV-2 RT-PCR systems in a very short time.
Emma Maury, Marc-Olivier Boldi, Gilbert Greub, Gilbert Greub, Valérie Chavez, Katia Jaton, Onya Opota   +6 more
doaj   +1 more source

Pages of the common history of Kazan and Saint Petersburg microbiology schools

Инфекция и иммунитет, 2023
The paper is prepared for the 100th anniversary of the Department of Microbiology at the Military Medical Academy and the 100th anniversary of naming Louis Pasteur Saint Petersburg Research Institute of Epidemiology and Microbiology.
Guzel S. Isaeva, Victor B. Sboychakov, Boris Yu. Gumilevsky   +2 more
doaj   +1 more source

Recent Advances in Applied Microbiology: Editorial

Microorganisms, 2020
The importance of microbiology has grown exponentially since the development of genomics, transcriptomics, and proteomics, making it possible to clarify microbial biogeochemical processes and their interactions with macroorganisms in both health and ...
Letícia M. Estevinho, Patrícia Combarros-Fuertes, Vanessa Branco Paula   +2 more
doaj   +1 more source

Ureteral Stent Microbiota Is Associated with Patient Comorbidities but Not Antibiotic Exposure

Cell Reports Medicine, 2020
Summary: Ureteral stents are commonly used to prevent urinary obstruction but can become colonized by bacteria and encrusted, leading to clinical complications.
Kait F. Al, John D. Denstedt, Brendan A. Daisley, Jennifer Bjazevic, Blayne K. Welk, Stephen E. Pautler, Gregory B. Gloor, Gregor Reid, Hassan Razvi, Jeremy P. Burton   +9 more
doaj   +1 more source

Pre-Medical Preparation in Microbiology among Applicants and Matriculants in Osteopathic Medical School in the United States

Journal of Microbiology & Biology Education, 2017
It is recognized that medical school curricula contain significant microbiology-related content as part of the training of future physicians who will be responsible stewards of antimicrobials.
Raddy L. Ramos, Erik Guercio, Luis R. Martinez   +2 more
doaj   +1 more source

Role of bacteriophages in STEC infections: new implications for the design of prophylactic and treatment approaches [v2; ref status: indexed, http://f1000r.es/437]

F1000Research, 2014
Shiga toxin (Stx) is considered the main virulence factor in Shiga toxin-producing Escherichia coli (STEC) infections. Previously we reported the expression of biologically active Stx by eukaryotic cells in vitro and in vivo following transfection with ...
Jaime H. Amorim, Manuel E. Del Cogliano, Romina J. Fernandez-Brando, Marcos F. Bilen, Monica R. Jesus, Wilson B. Luiz, Marina S. Palermo, Rita C.C. Ferreira, Esteban G. Servat, Pablo D. Ghiringhelli, Luis C.S Ferreira, Leticia V. Bentancor   +11 more
doaj   +1 more source

Transforming Medical Microbiology: The Role of Artificial Intelligence

Journal of Pure and Applied Microbiology
Traditional microbiological techniques, while effective, are often time-consuming and labour-intensive. Machine learning and deep learning, enable rapid and accurate identification of microbial pathogens from complex datasets such as whole-genome ...
Suvarna Sande, Manisha Rajguru
doaj   +1 more source