Results 111 to 120 of about 4,243,211 (352)

“Technology Proficiency” in Medical Education: Worthiness for Worldwide Wonderful Competency and Sophistication

, 2022
Sunil Jain, Bhagya Kamal Jain, Prem Kamal Jain, Vishal Marwaha   +3 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Extended reality and healthcare practitioner well-being: scoping review

BJPsych Open
Background Extended reality may offer a convenient and effective method of increasing well-being within the wider healthcare workforce and particularly for those working in the mental health sector who are subject to high levels of stress because of ...
Holly Mould, Jonathan R. Abbas, Michael Loizou, Nick Culley, Sheena Asthana, Rohit Shankar, John Downey   +6 more
doaj   +1 more source

Investigating scientific literacy: Scientist’s habits of mind as evidenced by their rationale of science and religious beliefs [PDF]

, 2006
Science and technology have been incredibly success¬ful in purely technical terms. For instance, international air travel, space flight, and curing of hitherto untreatable medical illnesses all are now routine events.
Coll, Richard K., Lay, Mark C., Mark C., Neil   +2 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Integrating mind, body, and technology: Building virtual psychosocial programs for medical populations [PDF]

, 2022
Victoria A. Grunberg, Ana‐Maria Vranceanu   +1 more
openalex   +1 more source

Wireless Handheld Computers in the Preclinical Undergraduate Curriculum [PDF]

, 2003
This report presents the results of a pilot project using wireless PDAs as teaching tools in an undergraduate medical curriculum. This technology was used to foster a transition from a passive to an interactive learning environment in the classroom and ...
Ganger BS, Anand C., Jackson Ph.D., Matt   +1 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Caring for children with new medical technology at home: parental perspectives. [PDF]

BMJ Paediatr Open, 2023
Pitch N, Shahil A, Mekhuri S, Ambreen M, Chu S, Keilty K, Cohen E, Orkin J, Amin R.   +8 more
europepmc   +1 more source

Biomedical applications team Quarterly progress report, 15 Dec. 1967 - 14 Mar. 1968 [PDF]

Transferring NASA generated technology into biological and medical research ...

core   +1 more source