Results 41 to 50 of about 14,941 (270)

Mineralizing Elastin‐Like Protein Microgels

Journal of Biomedical Materials Research Part A, Volume 113, Issue 12, December 2025.
ABSTRACT Mineralized tissues, such as bone and enamel are fundamental to the structure and function of organisms, with a complex interplay between their organic and inorganic components. Organized mineralization is crucial for both the tissues of living organisms and engineered materials.
Ieva Sapjanskaite, Abshar Hasan, José Carlos Rodríguez‐Cabello, Christopher Parmenter, Michael W. Fay, Christabel Fowler, Cameron Alexander, Alvaro Mata   +7 more
wiley   +1 more source

The role of bone marrow mononuclear cell-conditioned medium in the proliferation and migration of human dermal fibroblasts

Cellular & Molecular Biology Letters, 2017
Background Several recent studies have demonstrated the great potential of bone marrow cells in regenerative medicine, not only for their ability to differentiate to match a damaged cell type, but also because they synthesize and release various growth ...
Yolanda Menéndez-Menéndez, Jesús Otero-Hernández, Jose Antonio Vega, Marcos Pérez-Basterrechea, Silvia Pérez-López, María Álvarez-Viejo, Amaia Ferrero-Gutiérrez   +6 more
doaj   +1 more source

Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage

Microbial Cell, 2020
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair.
Pedro Ortega, Desiré García-Pichardo, Marta San Martin-Alonso, Ana G. Rondón, Belén Gómez-González, Andrés Aguilera   +5 more
doaj   +1 more source

Cèl·lules mare embrionàries i medicina regenerativa [PDF]

, 2012
Embryonary stem cells and Regenerative Medicine.Embryonary stem cells have represented a scientific revolution in recent years given their potential capacity to turn into any cell type in the organism.
Anna Veiga, Begoña Aran, Ignasi Rodríguez, Juan Carlos Izpisúa Belmonte, Ángel Raya   +4 more
core   +1 more source

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

eLife, 2020
DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with DNA:RNA hybrids being produced co-transcriptionally by the invasion of the nascent RNA molecule produced in cis with its DNA template.
Juan Lafuente-Barquero, Maria Luisa García-Rubio, Marta San Martin-Alonso, Belén Gómez-González, Andrés Aguilera   +4 more
doaj   +1 more source

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

Frontiers in Immunology, 2023
BackgroundNumerous lines of evidence confirm that decidual stromal cells (DSCs) play a key role in maternal–fetal immune tolerance. Under the influence of progesterone and other hormones, the DSCs go through a process of differentiation (decidualization)
Tatiana Llorca, Maria Jose Ruiz-Magaña, Rocio Martinez-Aguilar, Olga María García-Valdeavero, Lucia Rodríguez-Doña, Ana Clara Abadia-Molina, Ana Clara Abadia-Molina, Carmen Ruiz-Ruiz, Carmen Ruiz-Ruiz, Enrique G. Olivares, Enrique G. Olivares, Enrique G. Olivares   +11 more
doaj   +1 more source

Les cèl·lules mare arriben a Barcelona [PDF]

, 2015
Una de les tecnologies biomèdiques naixents més esperançadores i controvertides és sens dubte la clonació terapèutica, que utilitza cèl·lules mare d'embrions humans.
Bueno i Torrens, David, 1965-
core  

Adaptive Elastin‐Like Hydrogel with Unidirectional and Controllable Anisotropic Actuation for Soft Robotics and Tissue Engineering

Advanced Materials Technologies, Volume 10, Issue 17, September 4, 2025.
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio, Amanda Schmidt, Ikram El Maachi, Alexander Greenhalgh, Martin Frydrych, Stefan Jockenhoevel, José Carlos Rodríguez‐Cabello, Alicia Fernández‐Colino   +7 more
wiley   +1 more source

TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex

Non-Coding RNA, 2022
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (Lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT).
Salvador Polo-Generelo, Belén Torres, José A. Guerrero-Martínez, Emilio Camafeita, Jesús Vázquez, José C. Reyes, José A. Pintor-Toro   +6 more
doaj   +1 more source

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, Volume 47, Issue 8, August 2025.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source