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Feature Reviews in Medicinal Chemistry [PDF]

Pharmaceuticals
This Special Issue of Pharmaceuticals (“Feature reviews in Medicinal Chemistry”) contains a series of reviews covering a broad selection of topics in Medicinal Chemistry, which are chosen to illustrate important recent results in this fast-evolving ...
Mary J. Meegan
doaj   +2 more sources

Building a Medicinal Chemistry Framework for Bioorthogonal Probes. [PDF]

ACS Cent Sci
Staudt M, Carlson JCT.
europepmc   +2 more sources

Heterocycles in Medicinal Chemistry II [PDF]

Molecules
Carbon has a unique position among the elements, due to the fact that its valence shell has four electrons and is therefore quadrivalent in the excited state [...]
Josef Jampilek
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Medicinal Chemistry: Abstracts 63-97

CHIMIA, 2006
Swiss Chemical Society
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Medicinal Chemistry: A Key Driver in Achieving the Global Sustainable Development Goals. [PDF]

J Med Chem
Martinengo B, Diamanti E, Uliassi E, Bolognesi ML.   +3 more
europepmc   +3 more sources

[3 + n] Cycloaddition Reactions: A Milestone Approach for Elaborating Pyridazine of Potential Interest in Medicinal Chemistry and Optoelectronics

Molecules, 2021
During the last few decades, pyridazine derivatives have emerged as privileged structures in heterocyclic chemistry, both because of their excellent chemistry and because of their potential applications in medicinal chemistry and optoelectronics.
Dorina Amariucai-Mantu, Violeta Mangalagiu, Ionel I. Mangalagiu   +2 more
doaj   +1 more source

Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]

, 2016
The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA, Croft, RA, Davis, OA, Doran, R, Morgan, KF   +4 more
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Session Medicinal Chemistry Chemical Biology

CHIMIA, 2018
David Spichiger
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The Cu(OTf)2 catalysed microwave assisted synthesis of a new scaffold, 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-one [PDF]

, 2014
The synthesis of novel 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-ones is described including a one-step Mannich-type reaction followed by intramolecular ring closure of ethyl 3-methylpyridazine-4- carboxylate and aldimines, catalysed by the Lewis ...
De Coen, Laurens, Jatczak, Martyna, Mangelinckx, Sven, Muylaert, Koen, Stevens, Christian, Van Hecke, Kristof   +5 more
core   +2 more sources

Looking back and moving forward in medicinal chemistry

Nature Communications, 2023
Medicinal chemistry is a fast-evolving interdisciplinary research area which aims to improve human life by developing drugs to combat diseases. Nature Communications interviewed three scientists, Daniele Castagnolo (Associate Professor at University ...
doaj   +1 more source