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Molecular Filters in Medicinal Chemistry
Encyclopedia, 2023 Efficient chemical library design for high-throughput virtual screening and drug design requires a pre-screening filter pipeline capable of labeling aggregators, pan-assay interference compounds (PAINS), and rapid elimination of swill (REOS); identifying
Sebastjan Kralj +2 more
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New Trends in Synthetic Medicinal Chemistry. (Methods and Principles in Medicinal Chemistry, Volume 7) [PDF]
Molecules, 2001 n ...
Fulvio Gualtieri
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Feature Reviews in Medicinal Chemistry [PDF]
PharmaceuticalsThis Special Issue of Pharmaceuticals (“Feature reviews in Medicinal Chemistry”) contains a series of reviews covering a broad selection of topics in Medicinal Chemistry, which are chosen to illustrate important recent results in this fast-evolving ...
Mary J. Meegan
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Heterocycles in Medicinal Chemistry II [PDF]
MoleculesCarbon has a unique position among the elements, due to the fact that its valence shell has four electrons and is therefore quadrivalent in the excited state [...]
Josef Jampilek
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Pharmaceuticals, 2023 Artificial intelligence (AI) has permeated various sectors, including the pharmaceutical industry and research, where it has been utilized to efficiently identify new chemical entities with desirable properties.
Ri Han +4 more
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Pharmaceuticals, 2022 In this review, the history of boron’s early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed. This includes diazaborines, boronic acids, benzoxaboroles, boron clusters, and carboranes.
Katia Messner, Billy Vuong, G. Tranmer
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Decarboxylative Cross-Coupling: A Radical Tool in Medicinal Chemistry.
ACS Medicinal Chemistry Letters, 2022 Carboxylic acids, the most versatile and ubiquitous diversity input used in medicinal chemistry for canonical polar bond constructions such as amide synthesis, can now be employed in a fundamentally different category of reaction to make C-C bonds by ...
G. Laudadio +3 more
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Molecules, 2021 During the last few decades, pyridazine derivatives have emerged as privileged structures in heterocyclic chemistry, both because of their excellent chemistry and because of their potential applications in medicinal chemistry and optoelectronics.
Dorina Amariucai-Mantu +2 more
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Recent Advances of Pyridinone in Medicinal Chemistry
Frontiers in Chemistry, 2022 Pyridinones have been adopted as an important block in medicinal chemistry that could serve as hydrogen bond donors and acceptors. With the help of feasible synthesis routes via established condensation reactions, the physicochemical properties of such a
Shibo Lin +6 more
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