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Medicinal Chemistry of Isocyanides [PDF]
In eons of evolution, isocyanides carved out a niche in the ecological systems probably thanks to their metal coordinating properties. In 1859 the first isocyanide was synthesized by humans and in 1950 the first natural isocyanide was discovered. Now, at the beginning of XXI century, hundreds of isocyanides have been isolated both in prokaryotes and ...
Alberto Massarotti+4 more
openaire +6 more sources
Heterocycles in Medicinal Chemistry [PDF]
Heteroatoms constitute a very common fragment of a number of active pharmaceutical ingredients as well as excipients; from the point of view of significance, it is all the same if these are isosterically/bioisosterically replaced carbons/carbon ...
Josef Jampilek
doaj +3 more sources
Molecular Filters in Medicinal Chemistry
Efficient chemical library design for high-throughput virtual screening and drug design requires a pre-screening filter pipeline capable of labeling aggregators, pan-assay interference compounds (PAINS), and rapid elimination of swill (REOS); identifying
Sebastjan Kralj+2 more
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New Trends in Synthetic Medicinal Chemistry. (Methods and Principles in Medicinal Chemistry, Volume 7) [PDF]
n ...
Fulvio Gualtieri
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Feature Reviews in Medicinal Chemistry [PDF]
This Special Issue of Pharmaceuticals (“Feature reviews in Medicinal Chemistry”) contains a series of reviews covering a broad selection of topics in Medicinal Chemistry, which are chosen to illustrate important recent results in this fast-evolving ...
Mary J. Meegan
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Division of Medicinal Chemistry: Frontiers in Medicinal Chemistry
Swiss Chemical Society
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Heterocycles in Medicinal Chemistry II [PDF]
Carbon has a unique position among the elements, due to the fact that its valence shell has four electrons and is therefore quadrivalent in the excited state [...]
Josef Jampilek
doaj +2 more sources