Results 151 to 160 of about 1,354,772 (332)

Medicinal Chemistry: Abstracts 67-142

CHIMIA, 2010
Swiss Chemical Society
doaj   +1 more source

Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect

, 2019
Zefeng Zhao, Xufen Dai, Chenyang Li, Xiao Wang, Jiale Tian, Ying Feng, Jing Xie, Cong Ma, Zhuang Nie, Peinan Fan, Mingcheng Qian, Xirui He, Shaoping Wu, Yongmin Zhang, Xiaohui Zheng   +14 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Development in medicinal chemistry via oxadiazole derivatives: patent spotlight 2020–2024

Mehwish Solangi, Fouzia Naz, Syed Abid Ali, Khalid Mohammed Khan   +3 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Current Small Molecule–Based Medicinal Chemistry Approaches for Neurodegeneration Therapeutics [PDF]

Nitesh Sanghai, Billy Vuong, Ahmet Burak Berk, Muhammad Shaharyar K. Afridi, Geoffrey K. Tranmer   +4 more
openalex   +1 more source

Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors

, 2021
Arzu Gümüş, Murat Bozdağ, Andrea Angeli, Thomas S. Peat, Fabrizio Carta, Claudiu T. Supuran, Silvia Selleri   +6 more
openalex   +1 more source

The many facets of sustainability in medicinal chemistry: our personal experience. [PDF]

RSC Med Chem
Martinengo B, Diamanti E, Uliassi E, Bolognesi ML.   +3 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry. [PDF]

ChemistryOpen
Ten A, Koizhaiganova R, Bissenbay D, Tursynova B, Zhaxibayeva Z, Yu V.   +5 more
europepmc   +1 more source