Results 181 to 190 of about 33,369 (222)

Analysis of Familial Mediterranean Fever Gene Mutations in 202 Patients with Familial Mediterranean Fever

Genetic Testing, 2008
Familial Mediterranean fever (FMF) is an autosomal recessive disorder, caused by mutations in MEFV gene that encodes pyrin protein. In this study, we analyzed the most common five mutations in MEFV gene of 202 patients who were diagnosed formerly as FMF according to Tel-Hashomer criteria.
Mustafa, Solak, Handen, Yildiz, Resit, Koken, Muggan, Erdogan, Betul, Eser, Tolga, Sen, Neslihan, Evirgen, Solmaz, Erdem, Eurim, Arikan   +8 more
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Familial Mediterranean fever gene and protection against asthma

Annals of Allergy, Asthma & Immunology, 2007
Asthma is an inflammatory airway disease caused by interaction between susceptibility genes and diverse environmental factors. In Israel, asthma seems to be familial and more severe in patients of Iraqi Jewish descent. On the other hand, asthma is less frequent in individuals with familial Mediterranean fever, an autoinflammatory disease prevalent in ...
Einat, Rabinovitch, Dror, Harats, Pnina, Yaron, Tamar, Luvish, Merav, Lidar, Ron, Kedem, Aviv, Shaish, Issahar, Ben-Dov, Avi, Livneh   +8 more
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The Familial Mediterranean Fever Gene — Cloned at Last

New England Journal of Medicine, 1997
Familial Mediterranean fever is an inherited condition prevalent among people of the Near East — Arabs, Turks, Armenians, and Sephardic Jews.1 Transmitted as an autosomal recessive trait, familial ...
B M, Babior, Y, Matzner
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The clinical effect of gene mutations in familial Mediterranean fever disease

Pediatrics International, 2022
AbstractBackgroundFamilial Mediterranean fever (FMF) is a self‐limiting, autoinflammatory disease characterized by inflammation of the serosal surfaces and recurrent episodes of fever. The aim of this study is to determine the effect of genetic mutations on clinical features in children with FMF.MethodsA total of 303 patients aged 0–18 years, who were ...
Vildan Güngörer, Alaaddin Yorulmaz, Şükrü Arslan   +2 more
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Mapping of the Familial Mediterranean Fever Gene to Chromosome 16

American Journal of Reproductive Immunology, 1992
ABSTRACT: Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent attacks of fever, synovitis, peritonitis, or pleurisy. Some patients eventually develop systemic amyloidosis. The biochemical cause of the disease is unknown. We have conducted a genome‐wide search for the FMF locus using 125 different DNA markers
L, Gruberg, I, Aksentijevich, E, Pras, D L, Kastner, M, Pras   +4 more
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Common Familial Mediterranean Fever gene mutations in a Turkish cohort

Molecular Biology Reports, 2010
Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disorder with the responsible gene of MEFV which primarily affects Jewish, Armenian, Turkish and Arab populations. The FMF gene (MEFV) has recently been cloned to chromosome 16 p, which encodes pyrin.
DÜNDAR, Munis, BAŞKOL, Mevlüt, Kiraz, Aslıhan, Emirogullari, Elif Funda, TAHERİ, Serpil   +4 more
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R202Q homozygosity of Mediterranean fever gene is associated with atypical clinical phenotype of familial Mediterranean fever

European Journal of Internal Medicine
Apart from the classical phenotypes, familial Mediterranean fever (FMF) has several atypical manifestations making its diagnosis quite challenging. Our aim was to address the characteristics of FMF patients and the clinical importance of R202Q variant in a large cohort of patients from Greece.Prospectively collected data from 321 FMF patients were ...
Dimitrios Sagris, Christina Antoniadou, Nikolaos K. Gatselis, Efstratios Gavriilidis, Vasileios Papadopoulos, Sarah Georgiadou, Stella Gabeta, Victoria Tsironidou, Konstantinos P. Makaritsis, Panagiotis Skendros, Eirini I. Rigopoulou, Konstantinos Ritis, George N. Dalekos   +12 more
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MEFV Gene Mutations in Egyptian Patients with Familial Mediterranean Fever

Genetic Testing and Molecular Biomarkers, 2010
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and serositis. The disease affects mainly Mediterranean populations and is caused by mutations in the MEFV gene.This work was carried out to identify and determine the frequencies of MEFV gene mutations in Egyptian patients in whom FMF was ...
Dalal A, El Gezery, Abla A, Abou-Zeid, Doaa I, Hashad, Hesham K, El-Sayegh   +3 more
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Mediterranean fever gene variants and colchicine therapy in periodic fever, aphthous stomatitis pharyngitis, adenitis syndrome in a Mediterranean region.

Expert review of clinical immunology, 2019
PubMedID ...
Haytoglu Z., Gundeslioglu O.O.
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Amyloidosis of Familial Mediterranean Fever and theMEFVGene

Amyloid, 2000
(2000). Amyloidosis of Familial Mediterranean Fever and the MEFV Gene. Amyloid: Vol. 7, No. 4, pp. 289-293.
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