Results 81 to 90 of about 729,280 (261)

Eksperimentasi Model Pembelajaran Kooperatif Tipe Jigsaw Dan Group Investigation (Gi) Pada Pembelajaran Dimensi Tiga Siswa Kelas X SMA Negeri Se-kabupaten Wonogiri Ditinjau Dari Tingkat Kecerdasan Emosional Tahun Pelajaran 2012/2013 [PDF]

, 2014
The objectives of this research were to investigate: (1) which one providing better learning achievement, the Jigsaw learning model, GI or direct instruction; 2) which one having better learning achievement, the students with high, medium or low ...
Riyadi, R. (Riyadi), Sujadi, I. (Imam), Tarmo, T. (Tarmo)   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

From mother tongue to English: A language policy shift at a multilingual township school in Gauteng

South African Journal of Childhood Education
Background: Given the lack of research into English language instruction in multilingual contexts, this study explored the switch from mother tongue to English in a South African township school. Aim: This study aims to find out how teachers and parents
Rockie Sibanda, Lina P. Tshehla
doaj   +1 more source

English-medium instruction in European higher education: review and future research. [PDF]

, 2015
The purpose of this volume has been to give an account of the status of English as a medium of instruction in various political, geographical and ideological contexts: Northern, Southern, Eastern, Western and Central Europe, regions at different stages ...
Dimova, Slobodanka, Hultgren, Anna Kristina, Jensen, Christian   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Determinants of students' academic success in English as a medium of instruction (EMI) classes: A systematic review. [PDF]

Heliyon, 2023
Feng L, He L, Yiganmu A.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Multilingual medium of instruction towards an inclusive curriculum

Namibian Journal of Linguistics, Literature and Communication Studies
This study investigates the potential benefits of adopting a multilingual medium of instruction in Namibian schools in comparison to China's multilingual educational model. In Namibia, where English is the medium of instruction from grades 4 to 12, many
Salomo Ndeyamunye Ndeshimona
doaj   +1 more source