Results 21 to 30 of about 16,846 (220)

Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells [PDF]

open access: yes, 2021
This document is the Accepted Manuscript version of a published work that appeared in final form in Bioscience Reports. To access the final edited and published work see http://dx.doi.org/10.1042/BSR20202505Drug repurposing is a cost effective means of ...
Ellington, Max A.   +9 more
core   +1 more source

Progestins Inhibit Interleukin-1β-Induced Matrix Metalloproteinase 1 and Interleukin 8 Expression via the Glucocorticoid Receptor in Primary Human Amnion Mesenchymal Cells

open access: yesFrontiers in Physiology, 2020
Preterm premature rupture of membranes is a leading cause of preterm births. Cytokine induced matrix metalloproteinase1 and interleukin 8 production from amnion mesenchymal cells may contribute to fetal membrane weakening and rupture.
William Marinello   +2 more
doaj   +1 more source

Depot medroxyprogesterone: the way forward

open access: yes, 2020
India has a high rate of unintended pregnancies and abortions contribute to 8% of maternal mortality. The addition of injection depot medroxyprogesterone (DMPA) to the basket of contraceptives has allowed women to use a long-term contraceptive which does
Mehta, Sumita   +2 more
core   +1 more source

A Matched Case-Control Study Examining the Association Between Exposure to Depot Medroxyprogesterone Acetate and Cerebral Meningioma Using an Active Comparator

open access: yesCurrent Oncology
The recent literature has reported an increased association between the use of depot medroxyprogesterone acetate (dMPA) and cerebral meningioma (CM). Prior studies have been limited in generalizability and did not use an active comparator as a control ...
Russell Griffin, Rebecca Arend
doaj   +1 more source

Progestin-primed ovarian stimulation outcomes in in-vitro fertilization (IVF) – A systematic review of the literature

open access: yesGynecological Endocrinology
Background: Progestin-primed ovarian stimulation (PPOS) stimulates ovaries to block the premature surge of luteinizing hormone (LH) by using micronized progesterone or a progestin during the follicular phase instead of the conventional gonadotropin ...
Vyacheslav Notanovich Lokshin   +5 more
doaj   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni   +5 more
wiley   +1 more source

8-Chloro-cAMP-Related Changes on Mice Uteri

open access: yesThe Scientific World Journal, 2002
Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported.
Andrea Actis   +3 more
doaj   +1 more source

Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance

open access: yesHaematologica, 2010
Background Tumor cells in chronic lymphocytic leukemia accumulate in the periphery through the proliferation of a minority of cells in lymph nodes.
Rachel E. Hayden   +3 more
doaj   +1 more source

Association of novel intra‐cesarean post‐placental intrauterine device insertion techniques, and early ultrasound, with expulsion rates and strings visibility: A prospective exploratory study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess an innovative technique of intra‐cesarean post‐placental insertion of the Copper T380A IUD (CPPIUD), and explore the role of predischarge ultrasound with replacement of low‐lying IUDs. Methods We conducted a prospective observational study at Princess Marina Hospital, Gaborone, Botswana, from May 31, 2023, to April 3, 2024.
Kyungu M. Kime   +2 more
wiley   +1 more source

Distinct Solubilization Mechanisms of Medroxyprogesterone in Gemini Surfactant Micelles: A Comparative Study with Progesterone

open access: yesMolecules
The solubilization behavior of medroxyprogesterone (MP) within gemini surfactant micelles (14-6-14,2Br−) was investigated and compared with that of progesterone to uncover distinct solubilization mechanisms.
Hiromichi Nakahara   +2 more
doaj   +1 more source

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