Results 31 to 40 of about 13,629 (173)

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

iMeta, EarlyView.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang, Hongli Zhao, Xinyi Ding, Haoling Zhang, Yadong Guo, Yiming Ma, Lingyi Cai, Qingnan Fan, Ruisi Peng, Fuyuan Yang, Doblin Sandai, Xianling Cao, Jiali Yao, Wenyi Wang, Zhiheng Lin, Wangzheqi Zhang, Jialin He, Aihua Zhang, Xiaoxuan Zhao   +18 more
wiley   +1 more source

Evaluation of the effectiveness of medroxyprogesterone on blood gases and short-term hospital outcomes in patients with chronic obstructive pulmonary disease treating with noninvasive ventilation: A randomized clinical trial

Journal of Research in Medical Sciences
Background: In the present study, we aimed to evaluate the effects of medroxyprogesterone on hospital short clinical outcomes and ABG parameters in patients with chronic obstructive pulmonary disease (COPD) exacerbation under treatments with noninvasive ...
Somayeh Sadeghi, Farzin Ghiasi, Mohammad Emamiardestani, Mina Nickpour, Roham Gholami, Mohammad Saeid Khaksar, Masoud Mansouri   +6 more
doaj   +1 more source

Combined high dose vitamin C and E increases oxidative stress and visceral fat mass in rats treated by depot-medroxyprogesterone acetate

Middle East Fertility Society Journal, 2016
Objective: This study was aimed to investigate the effect of combined vitamin C and E on serum leptin, visceral fat mass, and visceral fat oxidative stress in rats treated by depot-medroxyprogesterone acetate (DMPA).
Endang Sri Wahyuni, I. Wayan Arsana Wiyasa, Nurdiana Nurdiana   +2 more
doaj   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan, Kelly M. Kons, Megan H. Fiorillo, Tonya S. Wright   +3 more
wiley   +1 more source

Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study

The Laryngoscope, EarlyView.
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian, Warren B. Chun, Shaun A. Nguyen, Ashli K. O'Rourke, Kirsten D. Meenan   +4 more
wiley   +1 more source

Long QTc Syndrome Type 2 Presenting in a Postpartum Patient on Medroxyprogesterone

Case Reports in Cardiology, 2014
Introduction. Congenital long QT syndrome type 2 (LQTS2) is a rare inherited cardiac abnormality resulting in increased risk of polymorphic ventricular tachycardia (PVT). Case Description.
John Kern, Margaret Duffy, Corinne Kern, Victor Mazza   +3 more
doaj   +1 more source

State Choices, Unequal Access: Policies Shaping Reproductive Health Care Across the United States

The Milbank Quarterly, EarlyView.
Policy Points State policies and programs play an outsized role in shaping availability and access to sexual and reproductive health services across the nation. This has a major impact on women's access to contraception, abortion, and maternity services.
ALINA SALGANICOFF, IVETTE GOMEZ, USHA RANJI   +2 more
wiley   +1 more source

Progestin-primed ovarian stimulation with letrozole using different doses of medroxyprogesterone acetate per day: a retrospective cohort study

Frontiers in Endocrinology
BackgroundIn the progestin-primed ovarian stimulation protocol, the oral administration of medroxyprogesterone acetate has been observed to effectively inhibit the LH surge during ovarian stimulation in patients experiencing infertility.
Hai-long Li, Hai-long Li, Hai-long Li, Bei-bei Shen, Bei-bei Shen, Bei-bei Shen, Zheng-liang He, Hai-li Wang, Zhi-feng Sun, Zhi-feng Sun, Zhi-feng Sun, Zhi-feng Sun, Zhi-feng Sun   +12 more
doaj   +1 more source

Efficacy of Different Progestins in Women With Advanced Endometriosis Undergoing Controlled Ovarian Hyperstimulation for in vitro Fertilization-A Single-Center Non-inferiority Randomized Controlled Trial

Frontiers in Endocrinology, 2020
Object: Is it possible to use different progestins cotreatment with human menopausal gonadotrophin (hMG) in women with advanced endometriosis but normal ovulation during controlled ovarian hyperstimulation (COH) in vitro fertilization (IVF)?
Haiyan Guo, Jianghui Li, Xi Shen, Yanyan Cong, Yun Wang, Ling Wu, Bin Li, Hongyuan Gao, Meng Ma, Wei Zhang, Xiaoyan Mao, Yonglun Fu, Qifeng Lyu, Weiran Chai, Yanping Kuang   +14 more
doaj   +1 more source