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Nonfamilial medullary thyroid carcinoma

The American Journal of Surgery, 1980
Abstract On the basis of this report and the current literature, we conclude that the familial type of medullary thyroid carcinoma can be diagnosed early using basal and poststimulation levels of calcitonin. However, most of the patients with sporadic disease present with a neck mass later in life.
R L, Rossi   +5 more
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Medullary thyroid carcinoma

Current Treatment Options in Oncology, 2003
Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all patients with the multiple endocrine neoplasia type 2 syndromes. MTCs produce calcitonin, the measurement of which can indicate the presence of tumors in people who are at risk and the ...
openaire   +2 more sources

FAMILIAL MEDULLARY THYROID CARCINOMA

The Lancet, 1978
Medullary thyroid carcinoma (M.C.T.) is a tumour of the calcitonin-secreting cells of the thyroid gland; it affects both lobes, has a variable malignant potential, and is often familial. Despite the availability of diagnostic plasma-calcitonin immunoassays, the condition is rarely considered in the initial assessment of a patient with a thyroid mass so
C J, Hillyard   +3 more
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Medullary Thyroid Carcinoma: Imaging

2015
Imaging plays an important role in early detection and staging of medullary thyroid carcinoma (MTC) as well as in follow-up to localize early recurrence. MTC is a rare, calcitonin-secreting thyroid malignancy often diagnosed by ultrasound and calcitonin screening as part of the routine workup for any thyroid nodule.
Stefan, Delorme, Friedhelm, Raue
openaire   +2 more sources

Medullary Thyroid Carcinoma in Children

2014
Medullary thyroid carcinoma (MTC) originates from thyroid parafollicular C cells, and it accounts for 5% of thyroid malignancies. MTC is sporadic in approximately 80% and hereditary in 20% of cases. When hereditary it can be associated with other benign endocrine neoplasias and/or typical nonendocrine diseases, thus configuring the multiple endocrine ...
VIOLA, DAVID   +2 more
openaire   +3 more sources

Medullary Thyroid Carcinoma

2012
Medullary thyroid carcinoma (MTC) originates from parafollicular cells (C-cells) of the thyroid gland. Calcitonin is a hormone secreted by parafollicular cells. The exact role of calcitonin is not understood, but it modulates bone mineral turnover. Medullary carcinoma accounts for less than 5 % of all thyroid cancers and is a clinically heterogeneous ...
Jean-François Chatal   +3 more
openaire   +2 more sources

Clinical utility of 177Lu‐DOTATATE PRRT in somatostatin receptor‐positive metastatic medullary carcinoma of thyroid patients with assessment of efficacy, survival analysis, prognostic variables, and toxicity

Head and Neck, 2019
The primary aim of this study was to evaluate the therapeutic efficacy and outcome of 177Lu‐DOTATATE peptide receptor radionuclide therapy (PRRT) in somatostatin receptor‐positive metastatic medullary thyroid carcinoma (MTC), including progression‐free ...
R. Parghane   +6 more
semanticscholar   +1 more source

Medullary Thyroid Carcinoma: Imaging

Imaging plays an important role in the early detection and staging of medullary thyroid carcinoma (MTC), as well as in follow-up to locate early recurrence. MTC is a rare, calcitonin-secreting thyroid malignancy that is often diagnosed by ultrasound and calcitonin screening as part of the routine evaluation of any thyroid nodule. If serum calcitonin is
Stefan, Delorme   +2 more
openaire   +2 more sources

[Medullary thyroid carcinoma].

Annales d'endocrinologie, 2008
Medullary thyroid carcinoma (MTC) is developed from thyroid C cells that secrete calcitonin (CT). MTC represents 5-10% of thyroid cancers with a 1-2% incidence in nodular thyroid diseases. Diagnosis is usually made by a solitary nodule often associated to nodal metastasis and confirmed by a high basal CT level which represents its biological marker ...
P, Niccoli-Sire, B, Conte-Devolx
openaire   +1 more source

Medullary Thyroid Carcinoma

Pathology Case Reviews, 2006
Medullary thyroid carcinoma (MTC) is currently defined as a malignant thyroid tumor with evidence of C-cell differentiation.1,2 While earlier reports had alluded to the existence of this tumor type, Robert Horn in 1951 reported a series of 7 cases of a thyroid cancer characterized by sharply defined rounded or ovoid compact cell groups of moderate size
openaire   +2 more sources

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