Results 91 to 100 of about 71,273 (273)
A novel role of HLA class I in the pathology of medulloblastoma
Journal of Translational Medicine, 2009 Background MHC class I expression by cancer cells enables specific antigen recognition by the immune system and protection of the host. However, in some cancer types MHC class I expression is associated with an unfavorable outcome.
Rood Brian R +8 more
doaj +1 more source
Nutrition in Clinical Practice, EarlyView.Abstract Background Diagnosing malnutrition in patients with pediatric cancer is challenging because tumor masses can interfere with anthropometric measurements. STRONGkids considers cancer a general risk factor, whereas Screening Tool for Childhood Cancer (SCAN) classifies patients as at risk or not, potentially missing those who need nutrition ...
Cristiane Ferreira Marçon +2 more
wiley +1 more source
Medulloblastoma – case presentation in an adult patient [PDF]
Romanian Journal of Neurology, 2015 The medulloblastoma is an infratentorial, rapidly growing embryonic tumor that arises in the posterior part of the cerebellar vermis and neuroepithelial roof of the fourth ventricle.
Adina Roceanu +2 more
doaj +1 more source
Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus. [PDF]
, 2017 Modified measles virus (MV) has effective oncolytic activity preclinically and is currently being investigated in clinical trials for various types of cancer. We investigated the use of cystine knot proteins (CKPs) to direct MV activity.
Lal, Sangeet, Raffel, Corey
core +2 more sources
Precision Radiation Oncology, EarlyView.• Objective: Assess helical Tomotherapy‐based TBI for clinical feasibility, dosimetric reproducibility, and in‐vivo accuracy using dual‐orientation simulation and patient‐specific QA. • Methodology: Implementation of ArcCHECK 3D diode array, ionization chamber verification, and in‐vivo dosimetry with OSLDs at 16 anatomical sites to ensure precise dose ...
Sandeep Singh +8 more
wiley +1 more source
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype [PDF]
, 2016 Hedgehog (Hh) inhibitors have emerged as valid tools in the treatment of a wide range of cancers. Indeed, aberrant activation of the Hh pathway occurring either by ligand-dependent or -independent mechanisms is a key driver in tumorigenesis.
Alfonsi, Romina +13 more
core +1 more source
Early Initiation of Adjuvant Therapy Following Pediatric Endoscopic Endonasal Surgery for Tumors
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective To evaluate complication rates of early adjuvant therapy initiation in pediatric patients with endoscopic endonasal resection for skull base tumors. Design Retrospective case series of pediatric patients (0–18 years old) with skull base tumors who underwent endoscopic endonasal resection between 2013 and 2023.
Heta Patel +7 more
wiley +1 more source
EXTH-81. ITGA5 IS A NOVEL IMMUNOTHERAPEUTIC TARGET AGAINST TREATMENT REFRACTORY MEDULLOBLASTOMA [PDF]
, 2022 David Bakhshinyan +10 more
openalex +1 more source
Brain Pathology, EarlyView.Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki +13 more
wiley +1 more source
CTIM-21. T-CELL RECEPTOR REPERTOIRE ANALYSIS IN PBMCS FROM PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA DURING ADOPTIVE CELLULAR THERAPY [PDF]
, 2023 Oleg Yegorov +3 more
openalex +1 more source